| Reaction Details |
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 | Report a problem with these data |
| Target | alpha-1,2-Mannosidase |
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| Ligand | BDBM50104309 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_32383 (CHEMBL646764) |
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| Ki | 170000±n/a nM |
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| Citation |  Popowycz, F; Gerber-Lemaire, S; Demange, R; Rodriguez-García, E; Asenjo, AT; Robina, I; Vogel, P Derivatives of (2R,3R,4S)-2-aminomethylpyrrolidine-3,4-diol are selective alpha-mannosidase inhibitors. Bioorg Med Chem Lett11:2489-93 (2001) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| |
| alpha-1,2-Mannosidase |
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| Name: | alpha-1,2-Mannosidase |
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| Synonyms: | Alpha-mannosidase |
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| Type: | PROTEIN |
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| Mol. Mass.: | 65344.50 |
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| Organism: | Glycine max |
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| Description: | ChEMBL_32380 |
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| Residue: | 578 |
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| Sequence: | MARGSRSVGSSSSKWRYCNPSYYLKRPKRLALLFIVFVCVSFVFWDRQTLVREHQVEISE
LQKEVTDLKNLVDDLNNKQGGTSGKTDLGRKATKSSKDVLDDPIDIERREKVKEAMLHAW
GSYEKYAWGQDELQPQSKNGVNSFGGLGATLIDSLDTLYIMGLNEQFQKAREWVANSLDF
NKDYEASVFETTIRVVGGLLSAYDLSGDKVFLDKAIEIADRLLPAWNTPTGIPYNIINLS
HGRAHNPSWTGGESILADSGTEQLEFIVLSQRTGDLKYQQKVENVIAQLNKTFPDDGLLP
IYINPHSGAAGYSPITFGAMGDSFYEYLLKVWIQGNKTSSIKHYRDMWEKSMKGLSSLIR
RSTPSSFTYICEKNGGSLTDKMDELACFAPGMIALGSFGYSAADDSQKFLSLAEELAWTC
YNFYQSTPTKLAGENYFFHSGQDMSVGTSWNILRPETVESLFYLWRLTGNKTYQEWGWNI
FQAFEKNSRIESGYVGLKDVNSGVKDNMMQSFFLAETLKYFYLLFSPSSVISLDEWVFNT
EAHPLRIVTRHEEGLVKNLNEKQKPFSRIGGRKEGRSG
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| BDBM50104309 |
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| n/a |
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| Name | BDBM50104309 |
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| Synonyms: | 2-[((R)-1-Phenyl-ethylamino)-methyl]-pyrrolidine-3,4-diol | CHEMBL309850 |
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| Type | Small organic molecule |
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| Emp. Form. | C13H20N2O2 |
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| Mol. Mass. | 236.3101 |
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| SMILES | C[C@@H](NCC1NCC(O)C1O)c1ccccc1 |
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| Structure | 
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