Reaction Details |
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Target | Serine protease 1 |
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Ligand | BDBM50111109 |
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Substrate/Competitor | n/a |
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Meas. Tech. | ChEBML_212195 |
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Ki | 2.9±n/a nM |
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Citation | Lee, K; Jung, WH; Park, CW; Park, HD; Lee, SH; Kwon, OH Noncovalent tripeptidic thrombin inhibitors incorporating amidrazone, amine and amidine functions at P1. Bioorg Med Chem Lett12:1017-22 (2002) [PubMed] |
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More Info.: | Get all data from this article, Assay Method |
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Serine protease 1 |
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Name: | Serine protease 1 |
Synonyms: | Beta-Trypsin | Cationic trypsin | PRSS1 | TRP1 | TRY1 | TRY1_BOVIN | TRYP1 | Trypsin | Trypsin I |
Type: | Enzyme |
Mol. Mass.: | 25790.52 |
Organism: | Bos taurus (bovine) |
Description: | P00760 |
Residue: | 246 |
Sequence: | MKTFIFLALLGAAVAFPVDDDDKIVGGYTCGANTVPYQVSLNSGYHFCGGSLINSQWVVS
AAHCYKSGIQVRLGEDNINVVEGNEQFISASKSIVHPSYNSNTLNNDIMLIKLKSAASLN
SRVASISLPTSCASAGTQCLISGWGNTKSSGTSYPDVLKCLKAPILSDSSCKSAYPGQIT
SNMFCAGYLEGGKDSCQGDSGGPVVCSGKLQGIVSWGSGCAQKNKPGVYTKVCNYVSWIK
QTIASN
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BDBM50111109 |
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n/a |
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Name | BDBM50111109 |
Synonyms: | {(R)-1-Benzhydryl-2-[(S)-2-(4-carbamimidoyl-benzylcarbamoyl)-pyrrolidin-1-yl]-2-oxo-ethyl}-phosphoramidic acid dimethyl ester; trifluoroacetate |
Type | Small organic molecule |
Emp. Form. | C30H36N5O6P |
Mol. Mass. | 593.6116 |
SMILES | COP([O-])([O-])(N[C@H](C(c1ccccc1)c1ccccc1)C(=O)N1CCC[C@H]1C(=O)NCc1ccc(cc1)C(N)=N)OC |
Structure |
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