| Reaction Details |
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 | Report a problem with these data |
| Target | C-C chemokine receptor type 3 |
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| Ligand | BDBM50133797 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEBML_41922 |
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| IC50 | >200000±n/a nM |
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| Citation |  Gong, L; Hogg, JH; Collier, J; Wilhelm, RS; Soderberg, C Design and synthesis of novel CCR3 antagonists. Bioorg Med Chem Lett13:3597-600 (2003) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| |
| C-C chemokine receptor type 3 |
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| Name: | C-C chemokine receptor type 3 |
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| Synonyms: | C-C CKR-3 | C-C chemokine receptor type 3 (CCR3) | CC-CKR-3 | CCR-3 | CCR3 | CCR3_HUMAN | CD_antigen=CD193 | CKR3 | CMKBR3 | Eosinophil eotaxin receptor |
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| Type: | Enzyme |
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| Mol. Mass.: | 41053.88 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P51677 |
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| Residue: | 355 |
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| Sequence: | MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILI
KYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSE
IFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEE
TLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRL
IFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVI
YAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF
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| BDBM50133797 |
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| n/a |
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| Name | BDBM50133797 |
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| Synonyms: | CHEMBL121743 | N-[1-(1-Benzyl-piperidin-4-ylmethyl)-2-methyl-propyl]-4-methyl-benzamide |
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| Type | Small organic molecule |
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| Emp. Form. | C25H34N2O |
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| Mol. Mass. | 378.5503 |
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| SMILES | CC(C)C(CC1CCN(Cc2ccccc2)CC1)NC(=O)c1ccc(C)cc1 |
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| Structure | 
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