| Reaction Details |
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 | Report a problem with these data |
| Target | Integrase |
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| Ligand | BDBM50079923 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_90870 (CHEMBL699303) |
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| IC50 | 331000±n/a nM |
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| Citation |  Mustata, GI; Brigo, A; Briggs, JM HIV-1 integrase pharmacophore model derived from diverse classes of inhibitors. Bioorg Med Chem Lett14:1447-54 (2004) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Integrase |
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| Name: | Integrase |
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| Synonyms: | Human immunodeficiency virus type 1 integrase |
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| Type: | PROTEIN |
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| Mol. Mass.: | 32231.48 |
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| Organism: | Human immunodeficiency virus 1 |
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| Description: | ChEMBL_90865 |
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| Residue: | 288 |
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| Sequence: | FLDGIDKAQDEHEKYHSNWRAMASDFNLPPVVAKEIVASCDKCQLKGEAMHGQVDCSPGI
WQLDCTHLEGKVILVAVHVASGYIEAEVIPAETGQETAYFLLKLAGRWPVKTIHTDNGSN
FTSTTVKAACWWAGIKQEFGIPYNPQSQGVVESMNKELKKIIGQVRDQAEHLKTAVQMAV
FIHNFKRKGGIGGYSAGERIVDIIATDIQTKELQKQITKIQNFRVYYRDSRDPLWKGPAK
LLWKGEGAVVIQDNSDIKVVPRRKVKIIRDYGKQMAGDDCVASRQDED
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| BDBM50079923 |
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| n/a |
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| Name | BDBM50079923 |
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| Synonyms: | 12,13-dimethoxy-5,9-dithia-3- azatricyclo[8.4.0.0³,⁷]tetradeca-1(14),10,12- triene-2,8-dione (Compound 8) | 6,7-Dimethoxy-1,10a-dihydro-2,9-dithia-3a-aza-benzo[f]azulene-4,10-dione | CHEMBL284144 |
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| Type | Small organic molecule |
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| Emp. Form. | C13H13NO4S2 |
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| Mol. Mass. | 311.377 |
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| SMILES | COc1cc2SC(=O)C3CSCN3C(=O)c2cc1OC |
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| Structure | 
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