| Reaction Details |
|---|
 | Report a problem with these data |
| Target | S-adenosylmethionine decarboxylase proenzyme |
|---|
| Ligand | BDBM28422 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_197052 (CHEMBL806291) |
|---|
| Ki | 60000±n/a nM |
|---|
| Citation |  Kolb, M; Danzin, C; Barth, J; Claverie, N Synthesis and biochemical properties of chemically stable product analogues of the reaction catalyzed by S-adenosyl-L-methionine decarboxylase. J Med Chem25:550-6 (1982) [PubMed] |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| S-adenosylmethionine decarboxylase proenzyme |
|---|
| Name: | S-adenosylmethionine decarboxylase proenzyme |
|---|
| Synonyms: | Amd1 | DCAM_RAT | S-adenosylmethionine decarboxylase 1 |
|---|
| Type: | PROTEIN |
|---|
| Mol. Mass.: | 38134.93 |
|---|
| Organism: | Rattus norvegicus |
|---|
| Description: | ChEMBL_197052 |
|---|
| Residue: | 333 |
|---|
| Sequence: | MEAAHFFEGTEKLLEVWFSRQQSDASQGSGDLRTIPRSEWDVLLKDVQCSIISVTKTDKQ
EAYVLSESSMFVSKRRFILKTCGTTLLLKALVPLLKLARDYSGFDSIQSFFYSRKNFMKP
SHQGYPHRNFQEEIEFLNAIFPNGAAYCMGRMNSDCWYLYTLDLPESRVINQPDQTLEIL
MSELDPAVMDQFYMKDGVTAKDVTRESGIRDLIPGSVIDATLFNPCGYSMNGMKSDGTYW
TIHITPEPEFSYVSFETNLSQTSYDDLIRKVVEVFKPGKFVTTLFVNQSSKCRTVLSSPQ
KIDGFKRLDCQSAMFNDYNFVFTSFAKKQQQQS
|
|
|
|---|
| BDBM28422 |
|---|
| n/a |
|---|
| Name | BDBM28422 |
|---|
| Synonyms: | (2S)-2-amino-4-({[(2S,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methyl}(methyl)sulfanylium)butanoate | AdoMet | S-Adenosylmethionine | S-adenosyl-L-[carboxy-14C]methionine | [14COOH]AdoMet |
|---|
| Type | radiolabeled substrate |
|---|
| Emp. Form. | C15H22N6O5S |
|---|
| Mol. Mass. | 398.437 |
|---|
| SMILES | C[S+](CC[C@H](N)C([O-])=O)C[C@H]1O[C@H]([C@H](O)[C@@H]1O)n1cnc2c(N)ncnc12 |
|---|
| Structure | 
|
|---|
Search and Browse
