Reaction Details |
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Target | Delta-type opioid receptor |
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Ligand | BDBM50021322 |
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Substrate/Competitor | n/a |
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Meas. Tech. | ChEMBL_146781 (CHEMBL754443) |
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Kd | 588±n/a nM |
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Citation | Cheng, A; Uyeno, E; Polgar, W; Toll, L; Lawson, JA; DeGraw, JI; Loew, G; Camerman, A; Camerman, N N-substituent modulation of opiate agonist/antagonist activity in resolved 3-methyl-3-(m-hydroxyphenyl)piperidines. J Med Chem29:531-7 (1986) [PubMed] |
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More Info.: | Get all data from this article, Assay Method |
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Delta-type opioid receptor |
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Name: | Delta-type opioid receptor |
Synonyms: | Cytochrome P450 3A4 | DOR-1 | Delta opioid receptor | Delta-type opioid receptor | Delta-type opioid receptor (DOR) | OPIATE Delta | OPRD_RAT | Opiate Delta 1 | Opioid receptor | Opioid receptor A | Opioid receptors; mu & delta | Oprd1 | Ror-a | Voltage-gated potassium channel |
Type: | G Protein-Coupled Receptor (GPCR) |
Mol. Mass.: | 40465.04 |
Organism: | Rattus norvegicus (rat) |
Description: | Competition binding assays were using CHO-K1 cell membranes expressing the opioid receptor. |
Residue: | 372 |
Sequence: | MEPVPSARAELQFSLLANVSDTFPSAFPSASANASGSPGARSASSLALAIAITALYSAVC
AVGLLGNVLVMFGIVRYTKLKTATNIYIFNLALADALATSTLPFQSAKYLMETWPFGELL
CKAVLSIDYYNMFTSIFTLTMMSVDRYIAVCHPVKALDFRTPAKAKLINICIWVLASGVG
VPIMVMAVTQPRDGAVVCTLQFPSPSWYWDTVTKICVFLFAFVVPILIITVCYGLMLLRL
RSVRLLSGSKEKDRSLRRITRMVLVVVGAFVVCWAPIHIFVIVWTLVDINRRDPLVVAAL
HLCIALGYANSSLNPVLYAFLDENFKRCFRQLCRAPCGGQEPGSLRRPRQATARERVTAC
TPSDGPGGGAAA
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BDBM50021322 |
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n/a |
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Name | BDBM50021322 |
Synonyms: | 3-(3-Methyl-1-phenethyl-piperidin-3-yl)-phenol | 3-(3-Methyl-1-phenethyl-piperidin-3-yl)-phenol:hydrochloricacid | CHEMBL150967 |
Type | Small organic molecule |
Emp. Form. | C20H25NO |
Mol. Mass. | 295.4186 |
SMILES | CC1(CCCN(CCc2ccccc2)C1)c1cccc(O)c1 |
Structure |
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