| Reaction Details |
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 | Report a problem with these data |
| Target | Thymidine kinase, cytosolic |
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| Ligand | BDBM50021776 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_207823 (CHEMBL812343) |
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| Ki | 45000±n/a nM |
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| Citation |  Mansuri, MM; Ghazzouli, I; Chen, MS; Howell, HG; Brodfuehrer, PR; Benigni, DA; Martin, JC 1-(2-Deoxy-2-fluoro-beta-D-arabinofuranosyl)-5-ethyluracil. A highly selective antiherpes simplex agent. J Med Chem30:867-71 (1987) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| |
| Thymidine kinase, cytosolic |
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| Name: | Thymidine kinase, cytosolic |
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| Synonyms: | KITH_HUMAN | TK1 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 25476.50 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_1333884 |
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| Residue: | 234 |
|---|
| Sequence: | MSCINLPTVLPGSPSKTRGQIQVILGPMFSGKSTELMRRVRRFQIAQYKCLVIKYAKDTR
YSSSFCTHDRNTMEALPACLLRDVAQEALGVAVIGIDEGQFFPDIVEFCEAMANAGKTVI
VAALDGTFQRKPFGAILNLVPLAESVVKLTAVCMECFREAAYTKRLGTEKEVEVIGGADK
YHSVCRLCYFKKASGQPAGPDNKENCPVPGKPGEAVAARKLFAPQQILQCSPAN
|
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|
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| BDBM50021776 |
|---|
| n/a |
|---|
| Name | BDBM50021776 |
|---|
| Synonyms: | 2-Amino-9-(2-hydroxy-ethoxymethyl)-5,9-dihydro-purin-6-one | 2-Amino-9-(2-hydroxy-ethoxymethyl)-5,9-dihydro-purin-6-one (ACV) | ACYCLOVIR | CHEMBL279075 |
|---|
| Type | Small organic molecule |
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| Emp. Form. | C8H11N5O3 |
|---|
| Mol. Mass. | 225.2046 |
|---|
| SMILES | Nc1nc2n(COCCO)cnc2c(=O)[nH]1 |
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| Structure | 
|
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