| Reaction Details |
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 | Report a problem with these data |
| Target | Lysosomal Pro-X carboxypeptidase |
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| Ligand | BDBM50017038 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEBML_154847 |
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| IC50 | 5300±n/a nM |
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| Citation |  Gray, NM; Cheng, BK; Mick, SJ; Lair, CM; Contreras, PC Phencyclidine-like effects of tetrahydroisoquinolines and related compounds. J Med Chem32:1242-8 (1989) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| Lysosomal Pro-X carboxypeptidase |
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| Name: | Lysosomal Pro-X carboxypeptidase |
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| Synonyms: | Angiotensinase C | Lysosomal carboxypeptidase C | PCP | PCP_HUMAN | PRCP | Proline carboxypeptidase | Prolylcarboxypeptidase | Prolylcarboxypeptidase (PRCP) |
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| Type: | Enzyme |
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| Mol. Mass.: | 55805.19 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P42785 |
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| Residue: | 496 |
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| Sequence: | MGRRALLLLLLSFLAPWATIALRPALRALGSLHLPTNPTSLPAVAKNYSVLYFQQKVDHF
GFNTVKTFNQRYLVADKYWKKNGGSILFYTGNEGDIIWFCNNTGFMWDVAEELKAMLVFA
EHRYYGESLPFGDNSFKDSRHLNFLTSEQALADFAELIKHLKRTIPGAENQPVIAIGGSY
GGMLAAWFRMKYPHMVVGALAASAPIWQFEDLVPCGVFMKIVTTDFRKSGPHCSESIHRS
WDAINRLSNTGSGLQWLTGALHLCSPLTSQDIQHLKDWISETWVNLAMVDYPYASNFLQP
LPAWPIKVVCQYLKNPNVSDSLLLQNIFQALNVYYNYSGQVKCLNISETATSSLGTLGWS
YQACTEVVMPFCTNGVDDMFEPHSWNLKELSDDCFQQWGVRPRPSWITTMYGGKNISSHT
NIVFSNGELDPWSGGGVTKDITDTLVAVTISEGAHHLDLRTKNALDPMSVLLARSLEVRH
MKNWIRDFYDSAGKQH
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| BDBM50017038 |
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| n/a |
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| Name | BDBM50017038 |
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| Synonyms: | 1-(4-Chloro-phenyl)-1,2,3,4-tetrahydro-isoquinoline | CHEMBL21920 |
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| Type | Small organic molecule |
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| Emp. Form. | C15H14ClN |
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| Mol. Mass. | 243.731 |
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| SMILES | Clc1ccc(cc1)C1NCCc2ccccc12 |
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| Structure | 
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