| Reaction Details |
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 | Report a problem with these data |
| Target | Sigma non-opioid intracellular receptor 1 |
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| Ligand | BDBM50009063 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEBML_201270 |
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| Ki | 429±n/a nM |
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| Citation |  Glennon, RA; Smith, JD; Ismaiel, AM; el-Ashmawy, M; Battaglia, G; Fischer, JB Identification and exploitation of the sigma-opiate pharmacophore. J Med Chem34:1094-8 (1991) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| Sigma non-opioid intracellular receptor 1 |
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| Name: | Sigma non-opioid intracellular receptor 1 |
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| Synonyms: | Aging-associated gene 8 protein | OPRS1 | SGMR1_HUMAN | SIG-1R | SIGMAR1 | SR-BP | SR31747-binding protein | SRBP | Sigma 1-type opioid receptor | Sigma opioid receptor | Sigma1R | hSigmaR1 |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 25124.85 |
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| Organism: | Homo sapiens (Human) |
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| Description: | Q99720 |
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| Residue: | 223 |
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| Sequence: | MQWAVGRRWAWAALLLAVAAVLTQVVWLWLGTQSFVFQREEIAQLARQYAGLDHELAFSR
LIVELRRLHPGHVLPDEELQWVFVNAGGWMGAMCLLHASLSEYVLLFGTALGSRGHSGRY
WAEISDTIISGTFHQWREGTTKSEVFYPGETVVHGPGEATAVEWGPNTWMVEYGRGVIPS
TLAFALADTVFSTQDFLTLFYTLRSYARGLRLELTTYLFGQDP
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| BDBM50009063 |
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| n/a |
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| Name | BDBM50009063 |
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| Synonyms: | (+)3-Allyl-6,11-dimethyl-1,2,3,4,5,6-hexahydro-2,6-methano-benzo[d]azocin-8-ol | 3-Allyl-6,11-dimethyl-1,2,3,4,5,6-hexahydro-2,6-methano-benzo[d]azocin-8-ol | 3-Allyl-8-hydroxy-6,11-dimethyl-1,2,3,4,5,6-hexahydro-2,6-methano-benzo[d]azocinium | CHEMBL274099 |
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| Type | Small organic molecule |
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| Emp. Form. | C17H23NO |
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| Mol. Mass. | 257.3706 |
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| SMILES | CC1C2Cc3ccc(O)cc3C1(C)CCN2CC=C |TLB:9:10:1:15.13.14,16:15:1:10.4.3| |
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| Structure | 
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