| Reaction Details |
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 | Report a problem with these data |
| Target | Gag-Pol polyprotein [489-587] |
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| Ligand | BDBM50009258 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_157875 (CHEMBL763270) |
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| Ki | 0.600000±n/a nM |
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| Citation |  Huff, JR HIV protease: a novel chemotherapeutic target for AIDS. J Med Chem34:2305-14 (1991) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| |
| Gag-Pol polyprotein [489-587] |
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| Name: | Gag-Pol polyprotein [489-587] |
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| Synonyms: | Human immunodeficiency virus type 1 protease | POL_HV1H2 | Pol polyprotein | gag-pol |
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| Type: | Enzyme Subunit |
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| Mol. Mass.: | 10781.16 |
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| Organism: | Human immunodeficiency virus type 1 |
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| Description: | P04585[489-587] |
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| Residue: | 99 |
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| Sequence: | PQVTLWQRPLVTIKIGGQLKEALLDTGADDTVLEEMSLPGRWKPKMIGGIGGFIKVRQYD
QILIEICGHKAIGTVLVGPTPVNIIGRNLLTQIGCTLNF
|
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| BDBM50009258 |
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| n/a |
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| Name | BDBM50009258 |
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| Synonyms: | 2-[1-[1-carbamoyl-2-methyl-(1S)-propylcarbamoyl]-2-methyl-(1S)-propylcarbamoyl]-3-phenylpropyl[2-phenyl-1-phenylcarboxamido-(1S)-ethyl]phosphinic acid | CHEMBL307236 |
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| Type | Small organic molecule |
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| Emp. Form. | C35H45N4O6P |
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| Mol. Mass. | 648.7288 |
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| SMILES | CC(C)[C@H](NC(=O)[C@@H](NC(=O)C(Cc1ccccc1)CP(O)(=O)[C@@H](Cc1ccccc1)NC(=O)c1ccccc1)C(C)C)C(N)=O |
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| Structure | 
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