Reaction Details |
| Report a problem with these data |
Target | Gag-Pol polyprotein [489-587] |
---|
Ligand | BDBM50009260 |
---|
Substrate/Competitor | n/a |
---|
Meas. Tech. | ChEMBL_159774 (CHEMBL763099) |
---|
IC50 | 0.780000±n/a nM |
---|
Citation | Huff, JR HIV protease: a novel chemotherapeutic target for AIDS. J Med Chem34:2305-14 (1991) [PubMed] |
---|
More Info.: | Get all data from this article, Assay Method |
---|
|
Gag-Pol polyprotein [489-587] |
---|
Name: | Gag-Pol polyprotein [489-587] |
Synonyms: | Human immunodeficiency virus type 1 protease | POL_HV1H2 | Pol polyprotein | gag-pol |
Type: | Enzyme Subunit |
Mol. Mass.: | 10781.16 |
Organism: | Human immunodeficiency virus type 1 |
Description: | P04585[489-587] |
Residue: | 99 |
Sequence: | PQVTLWQRPLVTIKIGGQLKEALLDTGADDTVLEEMSLPGRWKPKMIGGIGGFIKVRQYD
QILIEICGHKAIGTVLVGPTPVNIIGRNLLTQIGCTLNF
|
|
|
BDBM50009260 |
---|
n/a |
---|
Name | BDBM50009260 |
Synonyms: | 1N-[4-amino(imino)methylamino-1-carbamoylbutyl]-2-(1-{2-[1-(2-hydroxy-1-methylcarboxamidopropylcarboxamido)-2-methylbutylcarboxamido]hexylamino}pentylcarboxamido)pentanediamide | CHEMBL73875 |
Type | Small organic molecule |
Emp. Form. | C35H67N11O8 |
Mol. Mass. | 769.9754 |
SMILES | CCCC[C@H](CN[C@H](CCCC)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCCNC(N)=N)C(N)=O)NC(=O)[C@@H](NC(=O)[C@@H](NC(C)=O)[C@@H](C)O)[C@@H](C)CC |
Structure |
|