| Reaction Details |
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 | Report a problem with these data |
| Target | D(2) dopamine receptor |
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| Ligand | BDBM50000771 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEBML_62224 |
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| Ki | 1311±n/a nM |
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| Citation |  de Costa, B; Radesca, L; Dominguez, C; Di Paolo, L; Bowen, WD Synthesis and receptor binding properties of fluoro- and iodo-substituted high affinity sigma receptor ligands: identification of potential PET and SPECT sigma receptor imaging agents. J Med Chem35:2221-30 (1992) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| D(2) dopamine receptor |
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| Name: | D(2) dopamine receptor |
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| Synonyms: | DOPAMINE D2 | DOPAMINE D2 Long | DOPAMINE D2 Short | DRD2_RAT | Dopamine D2 receptor | Dopamine2-like | Drd2 |
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| Type: | G Protein-Coupled Receptor (GPCR) |
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| Mol. Mass.: | 50931.60 |
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| Organism: | Rattus norvegicus (rat) |
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| Description: | P61169 |
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| Residue: | 444 |
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| Sequence: | MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVS
REKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTA
SILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQN
ECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPL
KGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPP
SHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMS
RRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNS
AVNPIIYTTFNIEFRKAFMKILHC
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| BDBM50000771 |
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| n/a |
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| Name | BDBM50000771 |
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| Synonyms: | CHEMBL71049 | [2-(4,5-Dichloro-2-iodo-phenyl)-ethyl]-methyl-(2-pyrrolidin-1-yl-ethyl)-amine |
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| Type | Small organic molecule |
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| Emp. Form. | C15H21Cl2IN2 |
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| Mol. Mass. | 427.151 |
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| SMILES | CN(CCN1CCCC1)CCc1cc(Cl)c(Cl)cc1I |
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| Structure | 
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