Reaction Details |
| Report a problem with these data |
Target | 5-hydroxytryptamine receptor 2C |
---|
Ligand | BDBM50005259 |
---|
Substrate/Competitor | n/a |
---|
Meas. Tech. | ChEBML_1861 |
---|
Ki | 610±n/a nM |
---|
Citation | Glennon, RA; Raghupathi, R; Bartyzel, P; Teitler, M; Leonhardt, S Binding of phenylalkylamine derivatives at 5-HT1C and 5-HT2 serotonin receptors: evidence for a lack of selectivity. J Med Chem35:734-40 (1992) [PubMed] |
---|
More Info.: | Get all data from this article, Assay Method |
---|
|
5-hydroxytryptamine receptor 2C |
---|
Name: | 5-hydroxytryptamine receptor 2C |
Synonyms: | 5-HT2C | 5-hydroxytryptamine receptor 2C | 5-hydroxytryptamine receptor 2C (5HT2c) | 5HT2C_RAT | 5ht1c | Htr1c | Htr2c | Serotonin (5-HT) receptor | Serotonin receptor 2a and 2c (5HT2A and 5HT2C) |
Type: | Enzyme |
Mol. Mass.: | 51935.10 |
Organism: | Rattus norvegicus (Rat) |
Description: | P08909 |
Residue: | 460 |
Sequence: | MVNLGNAVRSLLMHLIGLLVWQFDISISPVAAIVTDTFNSSDGGRLFQFPDGVQNWPALS
IVVIIIMTIGGNILVIMAVSMEKKLHNATNYFLMSLAIADMLVGLLVMPLSLLAILYDYV
WPLPRYLCPVWISLDVLFSTASIMHLCAISLDRYVAIRNPIEHSRFNSRTKAIMKIAIVW
AISIGVSVPIPVIGLRDESKVFVNNTTCVLNDPNFVLIGSFVAFFIPLTIMVITYFLTIY
VLRRQTLMLLRGHTEEELANMSLNFLNCCCKKNGGEEENAPNPNPDQKPRRKKKEKRPRG
TMQAINNEKKASKVLGIVFFVFLIMWCPFFITNILSVLCGKACNQKLMEKLLNVFVWIGY
VCSGINPLVYTLFNKIYRRAFSKYLRCDYKPDKKPPVRQIPRVAATALSGRELNVNIYRH
TNERVARKANDPEPGIEMQVENLELPVNPSNVVSERISSV
|
|
|
BDBM50005259 |
---|
n/a |
---|
Name | BDBM50005259 |
Synonyms: | 2-(2-Methoxy-4-methyl-phenyl)-1-methyl-ethylamine | CHEMBL166040 |
Type | Small organic molecule |
Emp. Form. | C11H17NO |
Mol. Mass. | 179.2588 |
SMILES | COc1cc(C)ccc1CC(C)N |
Structure |
|