Reaction Details |
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Target | 5-hydroxytryptamine receptor 2C |
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Ligand | BDBM50005249 |
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Substrate/Competitor | n/a |
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Meas. Tech. | ChEBML_1861 |
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Ki | 14±n/a nM |
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Citation | Glennon, RA; Raghupathi, R; Bartyzel, P; Teitler, M; Leonhardt, S Binding of phenylalkylamine derivatives at 5-HT1C and 5-HT2 serotonin receptors: evidence for a lack of selectivity. J Med Chem35:734-40 (1992) [PubMed] |
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More Info.: | Get all data from this article, Assay Method |
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5-hydroxytryptamine receptor 2C |
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Name: | 5-hydroxytryptamine receptor 2C |
Synonyms: | 5-HT2C | 5-hydroxytryptamine receptor 2C | 5-hydroxytryptamine receptor 2C (5HT2c) | 5HT2C_RAT | 5ht1c | Htr1c | Htr2c | Serotonin (5-HT) receptor | Serotonin receptor 2a and 2c (5HT2A and 5HT2C) |
Type: | Enzyme |
Mol. Mass.: | 51935.10 |
Organism: | Rattus norvegicus (Rat) |
Description: | P08909 |
Residue: | 460 |
Sequence: | MVNLGNAVRSLLMHLIGLLVWQFDISISPVAAIVTDTFNSSDGGRLFQFPDGVQNWPALS
IVVIIIMTIGGNILVIMAVSMEKKLHNATNYFLMSLAIADMLVGLLVMPLSLLAILYDYV
WPLPRYLCPVWISLDVLFSTASIMHLCAISLDRYVAIRNPIEHSRFNSRTKAIMKIAIVW
AISIGVSVPIPVIGLRDESKVFVNNTTCVLNDPNFVLIGSFVAFFIPLTIMVITYFLTIY
VLRRQTLMLLRGHTEEELANMSLNFLNCCCKKNGGEEENAPNPNPDQKPRRKKKEKRPRG
TMQAINNEKKASKVLGIVFFVFLIMWCPFFITNILSVLCGKACNQKLMEKLLNVFVWIGY
VCSGINPLVYTLFNKIYRRAFSKYLRCDYKPDKKPPVRQIPRVAATALSGRELNVNIYRH
TNERVARKANDPEPGIEMQVENLELPVNPSNVVSERISSV
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BDBM50005249 |
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n/a |
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Name | BDBM50005249 |
Synonyms: | 2-(2,5-Dimethoxy-4-propyl-phenyl)-1-methyl-ethylamine | 2-(2,5-Dimethoxy-4-propyl-phenyl)-1-methyl-ethylamine(DOPR) | CHEMBL8569 | DOPR |
Type | Small organic molecule |
Emp. Form. | C14H23NO2 |
Mol. Mass. | 237.3379 |
SMILES | CCCc1cc(OC)c(CC(C)N)cc1OC |
Structure |
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