Reaction Details |
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Target | Serine protease 1 |
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Ligand | BDBM50037981 |
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Substrate/Competitor | n/a |
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Meas. Tech. | ChEMBL_212378 (CHEMBL878759) |
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Ki | 360±n/a nM |
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Citation | Hilpert, K; Ackermann, J; Banner, DW; Gast, A; Gubernator, K; Hadváry, P; Labler, L; Müller, K; Schmid, G; Tschopp, TB Design and synthesis of potent and highly selective thrombin inhibitors. J Med Chem37:3889-901 (1994) [PubMed] |
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More Info.: | Get all data from this article, Assay Method |
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Serine protease 1 |
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Name: | Serine protease 1 |
Synonyms: | Beta-Trypsin | Cationic trypsin | PRSS1 | TRP1 | TRY1 | TRY1_BOVIN | TRYP1 | Trypsin | Trypsin I |
Type: | Enzyme |
Mol. Mass.: | 25790.52 |
Organism: | Bos taurus (bovine) |
Description: | P00760 |
Residue: | 246 |
Sequence: | MKTFIFLALLGAAVAFPVDDDDKIVGGYTCGANTVPYQVSLNSGYHFCGGSLINSQWVVS
AAHCYKSGIQVRLGEDNINVVEGNEQFISASKSIVHPSYNSNTLNNDIMLIKLKSAASLN
SRVASISLPTSCASAGTQCLISGWGNTKSSGTSYPDVLKCLKAPILSDSSCKSAYPGQIT
SNMFCAGYLEGGKDSCQGDSGGPVVCSGKLQGIVSWGSGCAQKNKPGVYTKVCNYVSWIK
QTIASN
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BDBM50037981 |
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n/a |
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Name | BDBM50037981 |
Synonyms: | CHEMBL103102 | CHEMBL216318 | Piperidine-1-carboxamidine; compound with GENERIC INORGANIC NEUTRAL COMPONENT |
Type | Small organic molecule |
Emp. Form. | C6H13N3 |
Mol. Mass. | 127.1875 |
SMILES | NC(=N)N1CCCCC1 |
Structure |
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