Ki Summary

Reaction Details

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Target

E-selectin

Ligand

BDBM50050454

Substrate/Competitor

n/a

Meas. Tech.

ChEMBL_60884 (CHEMBL673531)

IC50

>1000000±n/a nM

Citation

Ohmoto, H; Nakamura, K; Inoue, T; Kondo, N; Inoue, Y; Yoshino, K; Kondo, H; Ishida, H; Kiso, M; Hasegawa, A Studies on selectin blocker. 1. Structure-activity relationships of sialyl Lewis X analogs. J Med Chem39:1339-43 (1996) [PubMed] Article

More Info.:

Get all data from this article, Assay Method

E-selectin

Name:

E-selectin

Synonyms:

ELAM1 | LYAM2_HUMAN | SELE | Selectin | Selectin E

Type:

PROTEIN

Mol. Mass.:

66642.96

Organism:

Homo sapiens (Human)

Description:

ChEMBL_1438995

Residue:

610

Sequence:

MIASQFLSALTLVLLIKESGAWSYNTSTEAMTYDEASAYCQQRYTHLVAIQNKEEIEYLN
SILSYSPSYYWIGIRKVNNVWVWVGTQKPLTEEAKNWAPGEPNNRQKDEDCVEIYIKREK
DVGMWNDERCSKKKLALCYTAACTNTSCSGHGECVETINNYTCKCDPGFSGLKCEQIVNC
TALESPEHGSLVCSHPLGNFSYNSSCSISCDRGYLPSSMETMQCMSSGEWSAPIPACNVV
ECDAVTNPANGFVECFQNPGSFPWNTTCTFDCEEGFELMGAQSLQCTSSGNWDNEKPTCK
AVTCRAVRQPQNGSVRCSHSPAGEFTFKSSCNFTCEEGFMLQGPAQVECTTQGQWTQQIP
VCEAFQCTALSNPERGYMNCLPSASGSFRYGSSCEFSCEQGFVLKGSKRLQCGPTGEWDN
EKPTCEAVRCDAVHQPPKGLVRCAHSPIGEFTYKSSCAFSCEEGFELHGSTQLECTSQGQ
WTEEVPSCQVVKCSSLAVPGKINMSCSGEPVFGTVCKFACPEGWTLNGSAARTCGATGHW
SGLLPTCEAPTESNIPLVAGLSAAGLSLLTLAPFLLWLRKCLRKAKKFVPASSCQSLESD
GSYQKPSYIL

BDBM50050454

n/a

Name

BDBM50050454

Synonyms:

CHEMBL177789 | O-(3-O-Sulfo-beta-D-galactopyranosyl)-(1-4)-O-[alpha-L-fucopyransyl-(1-3-)]-2-acetamido-1,5-anhydro-D-glucitol sodium salt

Type

Small organic molecule

Emp. Form.

C19H32NO17S

Mol. Mass.

578.519

SMILES

C[C@@H]1O[C@@H](O[C@@H]2[C@H](CO[C@H](CO)[C@H]2O[C@@H]2O[C@H](O)[C@H](OS([O-])(=O)=O)[C@H](O)[C@H]2O)NC(C)=O)[C@@H](O)[C@H](O)[C@@H]1O

Structure