| Reaction Details |
|---|
 | Report a problem with these data |
| Target | E-selectin |
|---|
| Ligand | BDBM50408430 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_199695 (CHEMBL802924) |
|---|
| IC50 | 13000±n/a nM |
|---|
| Citation |  Hiramatsu, Y; Moriyama, H; Kiyoi, T; Tsukida, T; Inoue, Y; Kondo, H Studies on selectin blockers. 6. Discovery of homologous fucose sugar unit necessary for E-selectin binding. J Med Chem41:2302-7 (1998) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| E-selectin |
|---|
| Name: | E-selectin |
|---|
| Synonyms: | ELAM1 | LYAM2_HUMAN | SELE | Selectin | Selectin E |
|---|
| Type: | PROTEIN |
|---|
| Mol. Mass.: | 66642.96 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | ChEMBL_1438995 |
|---|
| Residue: | 610 |
|---|
| Sequence: | MIASQFLSALTLVLLIKESGAWSYNTSTEAMTYDEASAYCQQRYTHLVAIQNKEEIEYLN
SILSYSPSYYWIGIRKVNNVWVWVGTQKPLTEEAKNWAPGEPNNRQKDEDCVEIYIKREK
DVGMWNDERCSKKKLALCYTAACTNTSCSGHGECVETINNYTCKCDPGFSGLKCEQIVNC
TALESPEHGSLVCSHPLGNFSYNSSCSISCDRGYLPSSMETMQCMSSGEWSAPIPACNVV
ECDAVTNPANGFVECFQNPGSFPWNTTCTFDCEEGFELMGAQSLQCTSSGNWDNEKPTCK
AVTCRAVRQPQNGSVRCSHSPAGEFTFKSSCNFTCEEGFMLQGPAQVECTTQGQWTQQIP
VCEAFQCTALSNPERGYMNCLPSASGSFRYGSSCEFSCEQGFVLKGSKRLQCGPTGEWDN
EKPTCEAVRCDAVHQPPKGLVRCAHSPIGEFTYKSSCAFSCEEGFELHGSTQLECTSQGQ
WTEEVPSCQVVKCSSLAVPGKINMSCSGEPVFGTVCKFACPEGWTLNGSAARTCGATGHW
SGLLPTCEAPTESNIPLVAGLSAAGLSLLTLAPFLLWLRKCLRKAKKFVPASSCQSLESD
GSYQKPSYIL
|
|
|
|---|
| BDBM50408430 |
|---|
| n/a |
|---|
| Name | BDBM50408430 |
|---|
| Synonyms: | CHEMBL2029023 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C44H83N3O11 |
|---|
| Mol. Mass. | 830.1433 |
|---|
| SMILES | CCCCCCCCCCCCCCC(CCCCCCCCCCCCCC)C(=O)N[C@@H](CO[C@@H]1O[C@@H](O)[C@@H](O)[C@H](O)[C@@H]1O)C(=O)NC(CCC(O)=O)C(=O)NC |
|---|
| Structure | 
|
|---|
Search and Browse
