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| Reaction Details | |||
|---|---|---|---|
 | Report a problem with these data | ||
| Target | Metabotropic glutamate receptor 1 | ||
| Ligand | BDBM50089909 | ||
| Substrate/Competitor | n/a | ||
| Meas. Tech. | ChEMBL_105708 (CHEMBL719076) | ||
| Ki | 350±n/a nM | ||
| Citation |  Bräuner-Osborne, H; Egebjerg, J; Nielsen, EO; Madsen, U; Krogsgaard-Larsen, P Ligands for glutamate receptors: design and therapeutic prospects. J Med Chem43:2609-45 (2000) [PubMed] | ||
| More Info.: | Get all data from this article, Assay Method | ||
| Metabotropic glutamate receptor 1 | |||
| Name: | Metabotropic glutamate receptor 1 | ||
| Synonyms: | GPRC1A | GRM1 | GRM1_HUMAN | MGLUR1 | Metabotropic Glutamate 1a | metabotropic glutamate 1 | ||
| Type: | Enzyme | ||
| Mol. Mass.: | 132358.19 | ||
| Organism: | Homo sapiens (Human) | ||
| Description: | Q13255 | ||
| Residue: | 1194 | ||
| Sequence: |
| ||
| BDBM50089909 | |||
| n/a | |||
| Name | BDBM50089909 | ||
| Synonyms: | 3-[1-Amino-1-carboxy-2-(9H-thioxanthen-9-yl)-ethyl]-cyclobutanecarboxylic acid(LY393675) | CHEMBL92162 | ||
| Type | Small organic molecule | ||
| Emp. Form. | C21H21NO4S | ||
| Mol. Mass. | 383.461 | ||
| SMILES | N[C@@](CC1c2ccccc2Sc2ccccc12)([C@@H]1C[C@@H](C1)C(O)=O)C(O)=O |wU:19.24,17.20,1.0,wD:1.1,(-1.1,-9.45,;.38,-9.45,;.38,-10.93,;.4,-12.48,;-.94,-13.25,;-2.28,-12.5,;-3.62,-13.28,;-3.6,-14.82,;-2.27,-15.58,;-.94,-14.81,;.4,-15.58,;1.74,-14.79,;3.09,-15.58,;4.45,-14.79,;4.43,-13.22,;3.09,-12.45,;1.74,-13.24,;.35,-6.51,;1.36,-5.43,;.28,-4.43,;-.73,-5.52,;.23,-2.96,;1.48,-2.17,;-1.08,-2.26,;1.67,-8.73,;1.29,-6.9,;3.27,-8.08,)| | ||
| Structure | 
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