| Reaction Details |
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 | Report a problem with these data |
| Target | D(4) dopamine receptor |
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| Ligand | BDBM50119387 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_60668 (CHEMBL671704) |
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| Ki | 78±n/a nM |
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| Citation |  Bettinetti, L; Schlotter, K; Hübner, H; Gmeiner, P Interactive SAR studies: rational discovery of super-potent and highly selective dopamine D3 receptor antagonists and partial agonists. J Med Chem45:4594-7 (2002) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| D(4) dopamine receptor |
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| Name: | D(4) dopamine receptor |
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| Synonyms: | D(2C) dopamine receptor | DOPAMINE D4 | DOPAMINE D4.2 | DOPAMINE D4.4 | DRD4 | DRD4_HUMAN | Dopamine D4 receptor |
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| Type: | Enzyme |
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| Mol. Mass.: | 48373.19 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P21917 |
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| Residue: | 419 |
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| Sequence: | MGNRSTADADGLLAGRGPAAGASAGASAGLAGQGAAALVGGVLLIGAVLAGNSLVCVSVA
TERALQTPTNSFIVSLAAADLLLALLVLPLFVYSEVQGGAWLLSPRLCDALMAMDVMLCT
ASIFNLCAISVDRFVAVAVPLRYNRQGGSRRQLLLIGATWLLSAAVAAPVLCGLNDVRGR
DPAVCRLEDRDYVVYSSVCSFFLPCPLMLLLYWATFRGLQRWEVARRAKLHGRAPRRPSG
PGPPSPTPPAPRLPQDPCGPDCAPPAPGLPRGPCGPDCAPAAPSLPQDPCGPDCAPPAPG
LPPDPCGSNCAPPDAVRAAALPPQTPPQTRRRRRAKITGRERKAMRVLPVVVGAFLLCWT
PFFVVHITQALCPACSVPPRLVSAVTWLGYVNSALNPVIYTVFNAEFRNVFRKALRACC
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| BDBM50119387 |
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| n/a |
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| Name | BDBM50119387 |
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| Synonyms: | CHEMBL140968 | N-(5-(4-(2-methoxyphenyl)piperazin-1-yl)pentyl)H-pyrazolo[1,5-a]pyridine-2-carboxamide | Pyrazolo[1,5-a]pyridine-2-carboxylic acid {5-[4-(2-methoxy-phenyl)-piperazin-1-yl]-pentyl}-amide |
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| Type | Small organic molecule |
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| Emp. Form. | C24H31N5O2 |
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| Mol. Mass. | 421.5352 |
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| SMILES | COc1ccccc1N1CCN(CCCCCNC(=O)c2cc3ccccn3n2)CC1 |
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| Structure | 
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