| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Transporter |
|---|
| Ligand | BDBM50098392 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_144977 (CHEMBL753709) |
|---|
| IC50 | 1110±n/a nM |
|---|
| Citation |  Kolhatkar, RB; Ghorai, SK; George, C; Reith, ME; Dutta, AK Interaction of cis-(6-benzhydrylpiperidin-3-yl)benzylamine analogues with monoamine transporters: structure-activity relationship study of structurally constrained 3,6-disubstituted piperidine analogues of (2,2-diphenylethyl)-[1-(4-fluorobenzyl)piperidin-4-ylmethyl]amine. J Med Chem46:2205-15 (2003) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Transporter |
|---|
| Name: | Transporter |
|---|
| Synonyms: | Monoamine transporters; Norepininephrine & dopamine | Norepinephrine Monoamine transporters |
|---|
| Type: | PROTEIN |
|---|
| Mol. Mass.: | 66787.87 |
|---|
| Organism: | Rattus norvegicus |
|---|
| Description: | ChEMBL_1463061 |
|---|
| Residue: | 597 |
|---|
| Sequence: | MVTRTRETWGKKIDFLLSVVGFAVDLANVWRFPYLCYKNGGGAFLIPYTLFLIIAGMPLF
YMELALGQFNREGAATVWKICPFFKGVGYAVILIALYVGFYYNVIIAWSLYYLFASFTLN
LPWTNCGHAWNSPNCTDPKLLNASVLGDHTKYSKYKFTPAAEFYERGVLHLHESSGIHDI
GLPQWQLLLCLMVVIVVLYVSLWKGVKTSGKVVWITATLPYFVLFVLLVHGVTLPGASNG
INAYLHIDFYRLKEATVWIDAATQIFFSLGAGFGVLIAFASYNKFDNNCYRDALLTSTIN
CVTSFISGFAIFSILGYMAHEHKVKIEDVATEGAGLVFVLYPEAISTLSGSTFWAVLFFL
MLLALGLDSSMGGMEAVITGLADDFQVLKRHRKLFTCAVTLGTFLLAMFCITKGGIYVLT
LLDTFAAGTSILFAVLMEAIGVSWFYGVDRFSNDIQQMMGFKPGLYWRLCWKFVSPAFLL
FVVVVSIINFKPLTYDDYVYPPWANWVGWGIALSSMILVPAYVIYKFFSIRGSLWERVAY
GITPENEHHLLALEIELSSLQSFVITSCPIDPLLSSFLFISCQKTLVFKKSGPAPLI
|
|
|
|---|
| BDBM50098392 |
|---|
| n/a |
|---|
| Name | BDBM50098392 |
|---|
| Synonyms: | (2,2-Diphenyl-ethyl)-[1-(4-fluoro-benzyl)-piperidin-4-ylmethyl]-amine | CHEMBL39262 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C27H31FN2 |
|---|
| Mol. Mass. | 402.5468 |
|---|
| SMILES | Fc1ccc(CN2CCC(CNCC(c3ccccc3)c3ccccc3)CC2)cc1 |
|---|
| Structure | 
|
|---|
Search and Browse
