| Reaction Details |
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 | Report a problem with these data |
| Target | Sterol O-acyltransferase 1 |
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| Ligand | BDBM22231 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_306084 (CHEMBL833585) |
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| IC50 | >1000000±n/a nM |
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| Citation |  Xu, MZ; Lee, WS; Kim, MJ; Park, DS; Yu, H; Tian, GR; Jeong, TS; Park, HY Acyl-CoA: cholesterol acyltransferase inhibitory activities of fatty acid amides isolated from Mylabris phalerate Pallas. Bioorg Med Chem Lett14:4277-80 (2004) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Sterol O-acyltransferase 1 |
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| Name: | Sterol O-acyltransferase 1 |
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| Synonyms: | ACAT-1 | Acact | Acat | Cholesterol acyltransferase 1 | SOAT1_RAT | Soat1 | Sterol O-acyltransferase, Soat |
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| Type: | PROTEIN |
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| Mol. Mass.: | 64165.56 |
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| Organism: | Rattus norvegicus |
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| Description: | ChEMBL_28796 |
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| Residue: | 545 |
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| Sequence: | MVGEETSLRNRLSRSAENPEQDEAQKNLLDTHRNGHITMKQLIAKKRQLAAEAEELKPLF
LKEVGCHFDDFVTNLIDKSASLDNGGCALTTFSILEEMKNNHRAKDLRAPPEQGKIFISR
RSLLDELFEVDHIRTIYHMFIALLIIFILSTLVVDYIDEGRLVLEFSLLAYAFGQFPIVI
WTWWAMFLSTLAIPYFLFQRWAHGYSKSSHPLIYSLIHGAFFLVFQLGILGFIPTYVVLA
YTLPPASRFILILEQIRLVMKAHSYVRENVPRVLSAAKEKSSTVPVPTVNQYLYFLFAPT
LIYRDSYPRTPTVRWGYVAMQFLQVFGCLFYVYYIFERLCAPLFRNIKQEPFSARVLVLC
VFNSILPGVLMLFLSFFAFLHCWLNAFAEMLRFGDRMFYKDWWNSTSYSNYYRTWNVVVH
DWLYYYVYKDLLWFFSKRFRPAAMLAVFALSAVVHEYALAVCLSYFYPVLFVLFMFFGMA
FNFIVNDSRKRPVWNIMVRASLFLGHGVILCFYSQEWYARQRCPLKNPTFLDYVRPRTWT
CRYVF
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| BDBM22231 |
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| n/a |
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| Name | BDBM22231 |
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| Synonyms: | (9Z,12Z)-octadeca-9,12-dienoic acid | CHEMBL267476 | Linoleic Acid | Linoleic acid (LA) |
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| Type | Unsaturated fatty acid |
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| Emp. Form. | C18H32O2 |
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| Mol. Mass. | 280.4455 |
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| SMILES | CCCCC\C=C/C\C=C/CCCCCCCC(O)=O |
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| Structure | 
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