| Reaction Details |
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 | Report a problem with these data |
| Target | MO15-related protein kinase Pfmrk |
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| Ligand | BDBM50154607 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_306159 (CHEMBL832347) |
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| IC50 | 18000±n/a nM |
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| Citation |  Bhattacharjee, AK; Geyer, JA; Woodard, CL; Kathcart, AK; Nichols, DA; Prigge, ST; Li, Z; Mott, BT; Waters, NC A three-dimensional in silico pharmacophore model for inhibition of Plasmodium falciparum cyclin-dependent kinases and discovery of different classes of novel Pfmrk specific inhibitors. J Med Chem47:5418-26 (2004) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| MO15-related protein kinase Pfmrk |
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| Name: | MO15-related protein kinase Pfmrk |
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| Synonyms: | Protein kinase Pfmrk |
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| Type: | PROTEIN |
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| Mol. Mass.: | 37992.30 |
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| Organism: | Plasmodium falciparum |
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| Description: | ChEMBL_640752 |
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| Residue: | 324 |
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| Sequence: | MENNSTERYIFKPNFLGEGSYGKVYKAYDTILKKEVAIKKMKLNEISNYIDDCGINFVLL
REIKIMKEIKHKNIMSALDLYCEKDYINLVMEIMDYDLSKIINRKIFLTDSQKKCILLQI
LNGLNVLHKYYFMHRDLSPANIFINKKGEVKLADFGLCTKYGYDMYSDKLFRDKYKKNLN
LTSKVVTLWYRAPELLLGSNKYNSSIDMWSFGCIFAELLLQKALFPGENEIDQLGKIFFL
LGTPNENNWPEALCLPLYTEFTKATKKDFKTYFKIDDDDCIDLLTSFLKLNAHERISAED
AMKHRYFFNDPLPCDISQLPFNDL
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| BDBM50154607 |
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| n/a |
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| Name | BDBM50154607 |
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| Synonyms: | (E)-1-(4-Nitro-phenyl)-3-pyridin-2-yl-propenone | CHEMBL187434 |
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| Type | Small organic molecule |
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| Emp. Form. | C14H10N2O3 |
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| Mol. Mass. | 254.2408 |
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| SMILES | [O-][N+](=O)c1ccc(cc1)C(=O)\C=C\c1ccccn1 |
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| Structure | 
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