| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Metabotropic glutamate receptor 4 |
|---|
| Ligand | BDBM50056272 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_310799 (CHEMBL835645) |
|---|
| EC50 | >100000±n/a nM |
|---|
| Citation |  Triballeau, N; Acher, F; Brabet, I; Pin, JP; Bertrand, HO Virtual screening workflow development guided by the"receiver operating characteristic" curve approach. Application to high-throughput docking on metabotropic glutamate receptor subtype 4. J Med Chem48:2534-47 (2005) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Metabotropic glutamate receptor 4 |
|---|
| Name: | Metabotropic glutamate receptor 4 |
|---|
| Synonyms: | GRM4_RAT | Gprc1d | Grm4 | Metabotropic glutamate receptor | Metabotropic glutamate receptor 4 (mGlu4) | Mglur4 | mGlu4 | metabotropic glutamate 4 | metabotropic glutamate 4a |
|---|
| Type: | Enzyme |
|---|
| Mol. Mass.: | 101849.79 |
|---|
| Organism: | Rattus norvegicus (Rat) |
|---|
| Description: | P31423 |
|---|
| Residue: | 912 |
|---|
| Sequence: | MSGKGGWAWWWARLPLCLLLSLYAPWVPSSLGKPKGHPHMNSIRIDGDITLGGLFPVHGR
GSEGKACGELKKEKGIHRLEAMLFALDRINNDPDLLPNITLGARILDTCSRDTHALEQSL
TFVQALIEKDGTEVRCGSGGPPIITKPERVVGVIGASGSSVSIMVANILRLFKIPQISYA
STAPDLSDNSRYDFFSRVVPSDTYQAQAMVDIVRALKWNYVSTLASEGSYGESGVEAFIQ
KSRENGGVCIAQSVKIPREPKTGEFDKIIKRLLETSNARGIIIFANEDDIRRVLEAARRA
NQTGHFFWMGSDSWGSKSAPVLRLEEVAEGAVTILPKRMSVRGFDRYFSSRTLDNNRRNI
WFAEFWEDNFHCKLSRHALKKGSHIKKCTNRERIGQDSAYEQEGKVQFVIDAVYAMGHAL
HAMHRDLCPGRVGLCPRMDPVDGTQLLKYIRNVNFSGIAGNPVTFNENGDAPGRYDIYQY
QLRNGSAEYKVIGSWTDHLHLRIERMQWPGSGQQLPRSICSLPCQPGERKKTVKGMACCW
HCEPCTGYQYQVDRYTCKTCPYDMRPTENRTSCQPIPIVKLEWDSPWAVLPLFLAVVGIA
ATLFVVVTFVRYNDTPIVKASGRELSYVLLAGIFLCYATTFLMIAEPDLGTCSLRRIFLG
LGMSISYAALLTKTNRIYRIFEQGKRSVSAPRFISPASQLAITFILISLQLLGICVWFVV
DPSHSVVDFQDQRTLDPRFARGVLKCDISDLSLICLLGYSMLLMVTCTVYAIKTRGVPET
FNEAKPIGFTMYTTCIVWLAFIPIFFGTSQSADKLYIQTTTLTVSVSLSASVSLGMLYMP
KVYIILFHPEQNVPKRKRSLKAVVTAATMSNKFTQKGNFRPNGEAKSELCENLETPALAT
KQTYVTYTNHAI
|
|
|
|---|
| BDBM50056272 |
|---|
| n/a |
|---|
| Name | BDBM50056272 |
|---|
| Synonyms: | (1S,2S,5R,6S)-2-Amino-bicyclo[3.1.0]hexane-2,6-dicarboxylic acid | (1S,2S,5R,6S)-2-aminobicyclo[3.1.0]hexane-2,6-dicarboxylic acid | (2S,6S)-2-Amino-bicyclo[3.1.0]hexane-2,6-dicarboxylic acid | 2-Amino-bicyclo[3.1.0]hexane-2,6-dicarboxylic acid | 2-Amino-bicyclo[3.1.0]hexane-2,6-dicarboxylic acid (LY 354740) | 2-Amino-bicyclo[3.1.0]hexane-2,6-dicarboxylic acid(LY354740) | CHEMBL8759 | LY-354740 | LY366563 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C8H11NO4 |
|---|
| Mol. Mass. | 185.1772 |
|---|
| SMILES | N[C@]1(CC[C@H]2[C@@H]([C@@H]12)C(O)=O)C(O)=O |r| |
|---|
| Structure | 
|
|---|
Search and Browse
