| Reaction Details |
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 | Report a problem with these data |
| Target | Muscarinic acetylcholine receptor M1 |
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| Ligand | BDBM50175152 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_326610 (CHEMBL863453) |
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| Ki | 413±n/a nM |
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| Citation |  Grundt, P; Kopajtic, TA; Katz, JL; Newman, AH N-8-Substituted benztropinamine analogs as selective dopamine transporter ligands. Bioorg Med Chem Lett15:5419-23 (2005) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Muscarinic acetylcholine receptor M1 |
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| Name: | Muscarinic acetylcholine receptor M1 |
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| Synonyms: | ACM1_HUMAN | CHRM1 | Cholinergic receptor, muscarinic 1 | Cholinergic, muscarinic M1 |
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| Type: | Protein |
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| Mol. Mass.: | 51442.54 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P11229 |
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| Residue: | 460 |
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| Sequence: | MNTSAPPAVSPNITVLAPGKGPWQVAFIGITTGLLSLATVTGNLLVLISFKVNTELKTVN
NYFLLSLACADLIIGTFSMNLYTTYLLMGHWALGTLACDLWLALDYVASNASVMNLLLIS
FDRYFSVTRPLSYRAKRTPRRAALMIGLAWLVSFVLWAPAILFWQYLVGERTVLAGQCYI
QFLSQPIITFGTAMAAFYLPVTVMCTLYWRIYRETENRARELAALQGSETPGKGGGSSSS
SERSQPGAEGSPETPPGRCCRCCRAPRLLQAYSWKEEEEEDEGSMESLTSSEGEEPGSEV
VIKMPMVDPEAQAPTKQPPRSSPNTVKRPTKKGRDRAGKGQKPRGKEQLAKRKTFSLVKE
KKAARTLSAILLAFILTWTPYNIMVLVSTFCKDCVPETLWELGYWLCYVNSTINPMCYAL
CNKAFRDTFRLLLLCRWDKRRWRKIPKRPGSVHRTPSRQC
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| BDBM50175152 |
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| n/a |
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| Name | BDBM50175152 |
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| Synonyms: | 8-(2-(1H-indol-3-yl)ethyl)-N-(bis(4-fluorophenyl)methyl)-8-aza-bicyclo[3.2.1]octan-3-amine | CHEMBL197384 |
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| Type | Small organic molecule |
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| Emp. Form. | C30H31F2N3 |
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| Mol. Mass. | 471.584 |
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| SMILES | Fc1ccc(cc1)C(NC1CC2CCC(C1)N2CCc1c[nH]c2ccccc12)c1ccc(F)cc1 |TLB:8:9:12.13:16| |
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| Structure | 
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