| Reaction Details |
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 | Report a problem with these data |
| Target | Neurotensin receptor type 1 |
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| Ligand | BDBM50191591 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_376964 (CHEMBL870326) |
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| IC50 | 1.5±n/a nM |
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| Citation |  Nock, BA; Nikolopoulou, A; Reubi, JC; Maes, V; Conrath, P; Tourwé, D; Maina, T Toward stable N4-modified neurotensins for NTS1-receptor-targeted tumor imaging with 99mTc. J Med Chem49:4767-76 (2006) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Neurotensin receptor type 1 |
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| Name: | Neurotensin receptor type 1 |
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| Synonyms: | Dopamine receptor D2L/neurotensin receptor NTS1 | NTR1_HUMAN | NTRR | NTSR1 | Neurotensin receptor 1 | neurotensin receptor type 1 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 46278.89 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_1453811 |
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| Residue: | 418 |
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| Sequence: | MRLNSSAPGTPGTPAADPFQRAQAGLEEALLAPGFGNASGNASERVLAAPSSELDVNTDI
YSKVLVTAVYLALFVVGTVGNTVTAFTLARKKSLQSLQSTVHYHLGSLALSDLLTLLLAM
PVELYNFIWVHHPWAFGDAGCRGYYFLRDACTYATALNVASLSVERYLAICHPFKAKTLM
SRSRTKKFISAIWLASALLAVPMLFTMGEQNRSADGQHAGGLVCTPTIHTATVKVVIQVN
TFMSFIFPMVVISVLNTIIANKLTVMVRQAAEQGQVCTVGGEHSTFSMAIEPGRVQALRH
GVRVLRAVVIAFVVCWLPYHVRRLMFCYISDEQWTPFLYDFYHYFYMVTNALFYVSSTIN
PILYNLVSANFRHIFLATLACLCPVWRRRRKRPAFSRKADSVSSNHTLSSNATRETLY
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| BDBM50191591 |
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| n/a |
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| Name | BDBM50191591 |
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| Synonyms: | CHEMBL219862 | Demotensin 3 |
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| Type | Small organic molecule |
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| Emp. Form. | C48H87N15O9 |
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| Mol. Mass. | 1018.2995 |
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| SMILES | [#6]-[#6](-[#6])-[#6]-[#6@H](-[#7]-[#6](=O)-[#6@@H](-[#7]-[#6](=O)-[#6@H](-[#6]-c1ccc(-[#8])cc1)-[#7]-[#6](=O)-[#6@@H]-1-[#6]-[#6]-[#6]-[#7]-1-[#6](=O)-[#6@H](-[#6]-[#6]-[#6]\[#7]=[#6](/[#7])-[#7])-[#7]-[#6]-[#6](-[#6]-[#6]-[#6]-[#6]-[#7])-[#7]-[#6](=O)-[#6]-[#7]-[#6](=O)-[#6](-[#6]-[#7]-[#6]-[#6]-[#7])-[#6]-[#7]-[#6]-[#6]-[#7])C([#6])([#6])[#6])-[#6](-[#8])=O |
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| Structure | 
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