| Reaction Details |
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 | Report a problem with these data |
| Target | Cannabinoid receptor 1 |
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| Ligand | BDBM50195526 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_414848 (CHEMBL855029) |
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| Ki | >1000±n/a nM |
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| Citation |  Manera, C; Benetti, V; Castelli, MP; Cavallini, T; Lazzarotti, S; Pibiri, F; Saccomanni, G; Tuccinardi, T; Vannacci, A; Martinelli, A; Ferrarini, PL Design, synthesis, and biological evaluation of new 1,8-naphthyridin-4(1H)-on-3-carboxamide and quinolin-4(1H)-on-3-carboxamide derivatives as CB2 selective agonists. J Med Chem49:5947-57 (2006) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Cannabinoid receptor 1 |
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| Name: | Cannabinoid receptor 1 |
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| Synonyms: | Brain-type cannabinoid receptor | CANNABINOID CB1 | CB-R | CB1 | CNR1_MOUSE | Cannabinoid CB1 receptor | Cannabinoid receptor | Cnr1 |
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| Type: | Enzyme |
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| Mol. Mass.: | 52842.52 |
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| Organism: | Mus musculus (Mouse) |
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| Description: | P47746 |
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| Residue: | 473 |
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| Sequence: | MKSILDGLADTTFRTITTDLLYVGSNDIQYEDIKGDMASKLGYFPQKFPLTSFRGSPFQE
KMTAGDNSPLVPAGDTTNITEFYNKSLSSFKENEDNIQCGENFMDMECFMILNPSQQLAI
AVLSLTLGTFTVLENLLVLCVILHSRSLRCRPSYHFIGSLAVADLLGSVIFVYSFVDFHV
FHRKDSPNVFLFKLGGVTASFTASVGSLFLTAIDRYISIHRPLAYKRIVTRPKAVVAFCL
MWTIAIVIAVLPLLGWNCKKLQSVCSDIFPLIDETYLMFWIGVTSVLLLFIVYAYMYILW
KAHSHAVRMIQRGTQKSIIIHTSEDGKVQVTRPDQARMDIRLAKTLVLILVVLIICWGPL
LAIMVYDVFGKMNKLIKTVFAFCSMLCLLNSTVNPIIYALRSKDLRHAFRSMFPSCEGTA
QPLDNSMGDSDCLHKHANNTASMHRAAESCIKSTVKIAKVTMSVSTDTSAEAL
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| BDBM50195526 |
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| n/a |
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| Name | BDBM50195526 |
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| Synonyms: | CHEMBL385508 | N-cyclopentyl-7-methyl-1-(2-morpholin-4-ylethyl)-1,8-naphthyridin-4(1H)-on-3-carboxamide |
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| Type | Small organic molecule |
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| Emp. Form. | C21H28N4O3 |
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| Mol. Mass. | 384.472 |
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| SMILES | Cc1ccc2c(n1)n(CCN1CCOCC1)cc(C(=O)NC1CCCC1)c2=O |
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| Structure | 
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