Reaction Details |
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Target | Peptide deformylase 1A, chloroplastic/mitochondrial |
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Ligand | BDBM50201884 |
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Substrate/Competitor | n/a |
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Meas. Tech. | ChEMBL_423228 (CHEMBL912247) |
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IC50 | 14000±n/a nM |
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Citation | Boularot, A; Giglione, C; Petit, S; Duroc, Y; Alves de Sousa, R; Larue, V; Cresteil, T; Dardel, F; Artaud, I; Meinnel, T Discovery and refinement of a new structural class of potent peptide deformylase inhibitors. J Med Chem50:10-20 (2007) [PubMed] Article |
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More Info.: | Get all data from this article, Assay Method |
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Peptide deformylase 1A, chloroplastic/mitochondrial |
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Name: | Peptide deformylase 1A, chloroplastic/mitochondrial |
Synonyms: | AtDEF1 | AtDEF1A | DEF1 | DEF1A_ARATH | PDF 1A | PDF1A | Peptide deformylase 1A, chloroplastic | Polypeptide deformylase |
Type: | PROTEIN |
Mol. Mass.: | 30001.50 |
Organism: | Arabidopsis thaliana |
Description: | ChEMBL_423228 |
Residue: | 269 |
Sequence: | MGLHRDEATAMETLFRVSLRLLPVSAAVTCRSIRFPVSRPGSSHLLNRKLYNLPTSSSSS
LSTKAGWLLGLGEKKKKVDLPEIVASGDPVLHEKAREVDPGEIGSERIQKIIDDMIKVMR
LAPGVGLAAPQIGVPLRIIVLEDTKEYISYAPKEEILAQERRHFDLMVMVNPVLKERSNK
KALFFEGCLSVDGFRAAVERYLEVVVTGYDRQGKRIEVNASGWQARILQHECDHLDGNLY
VDKMVPRTFRTVDNLDLPLAEGCPKLGPQ
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BDBM50201884 |
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n/a |
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Name | BDBM50201884 |
Synonyms: | 5-bromo-3-hydroxycarbamoylmethylindole-1-carboxylic acid | CHEMBL386468 |
Type | Small organic molecule |
Emp. Form. | C19H17BrN2O4 |
Mol. Mass. | 417.253 |
SMILES | ONCC(=O)Cc1cn(C(=O)OCc2ccccc2)c2ccc(Br)cc12 |
Structure |
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