| Reaction Details |
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 | Report a problem with these data |
| Target | UDP-glucuronosyltransferase 2B7 |
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| Ligand | BDBM50370965 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_436438 (CHEMBL904746) |
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| IC50 | 5000±n/a nM |
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| Citation |  Bichlmaier, I; Kurkela, M; Joshi, T; Siiskonen, A; Rüffer, T; Lang, H; Suchanova, B; Vahermo, M; Finel, M; Yli-Kauhaluoma, J Isoform-selective inhibition of the human UDP-glucuronosyltransferase 2B7 by isolongifolol derivatives. J Med Chem50:2655-64 (2007) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| UDP-glucuronosyltransferase 2B7 |
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| Name: | UDP-glucuronosyltransferase 2B7 |
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| Synonyms: | 2.4.1.17 | 3,4-catechol estrogen-specific UDPGT | UD2B7_HUMAN | UDP-glucuronosyltransferase 2B7 | UDP-glucuronosyltransferase 2B9 | UDPGT 2B7 | UDPGT 2B9 | UDPGTh-2 | UGT2B7 | UGTB2B9 | Uridine-5'-diphosphoglucuronosyltransferase 2B7 |
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| Type: | Enzyme |
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| Mol. Mass.: | 60705.98 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P16662 |
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| Residue: | 529 |
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| Sequence: | MSVKWTSVILLIQLSFCFSSGNCGKVLVWAAEYSHWMNIKTILDELIQRGHEVTVLASSA
SILFDPNNSSALKIEIYPTSLTKTELENFIMQQIKRWSDLPKDTFWLYFSQVQEIMSIFG
DITRKFCKDVVSNKKFMKKVQESRFDVIFADAIFPCSELLAELFNIPFVYSLSFSPGYTF
EKHSGGFIFPPSYVPVVMSELTDQMTFMERVKNMIYVLYFDFWFEIFDMKKWDQFYSEVL
GRPTTLSETMGKADVWLIRNSWNFQFPYPLLPNVDFVGGLHCKPAKPLPKEMEDFVQSSG
ENGVVVFSLGSMVSNMTEERANVIASALAQIPQKVLWRFDGNKPDTLGLNTRLYKWIPQN
DLLGHPKTRAFITHGGANGIYEAIYHGIPMVGIPLFADQPDNIAHMKARGAAVRVDFNTM
SSTDLLNALKRVINDPSYKENVMKLSRIQHDQPVKPLDRAVFWIEFVMRHKGAKHLRVAA
HDLTWFQYHSLDVIGFLLVCVATVIFIVTKCCLFCFWKFARKAKKGKND
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| BDBM50370965 |
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| n/a |
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| Name | BDBM50370965 |
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| Synonyms: | CHEMBL1203943 |
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| Type | Small organic molecule |
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| Emp. Form. | C18H33N |
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| Mol. Mass. | 263.4613 |
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| SMILES | CN(C)CC[C@H]1[C@H]2CC[C@@H]3[C@H]2C(C)(C)CCC[C@]13C |r,TLB:18:17:7.8:10,8:9:5.6:11.14.15.16,THB:16:17:7.8:10,4:5:7.8:10,11:10:7.8:5.17| |
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| Structure | 
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