| Reaction Details |
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 | Report a problem with these data |
| Target | UDP-glucuronosyltransferase 2B7 |
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| Ligand | BDBM50211771 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_436438 (CHEMBL904746) |
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| IC50 | 4000±n/a nM |
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| Citation |  Bichlmaier, I; Kurkela, M; Joshi, T; Siiskonen, A; Rüffer, T; Lang, H; Suchanova, B; Vahermo, M; Finel, M; Yli-Kauhaluoma, J Isoform-selective inhibition of the human UDP-glucuronosyltransferase 2B7 by isolongifolol derivatives. J Med Chem50:2655-64 (2007) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| UDP-glucuronosyltransferase 2B7 |
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| Name: | UDP-glucuronosyltransferase 2B7 |
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| Synonyms: | 2.4.1.17 | 3,4-catechol estrogen-specific UDPGT | UD2B7_HUMAN | UDP-glucuronosyltransferase 2B7 | UDP-glucuronosyltransferase 2B9 | UDPGT 2B7 | UDPGT 2B9 | UDPGTh-2 | UGT2B7 | UGTB2B9 | Uridine-5'-diphosphoglucuronosyltransferase 2B7 |
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| Type: | Enzyme |
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| Mol. Mass.: | 60705.98 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P16662 |
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| Residue: | 529 |
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| Sequence: | MSVKWTSVILLIQLSFCFSSGNCGKVLVWAAEYSHWMNIKTILDELIQRGHEVTVLASSA
SILFDPNNSSALKIEIYPTSLTKTELENFIMQQIKRWSDLPKDTFWLYFSQVQEIMSIFG
DITRKFCKDVVSNKKFMKKVQESRFDVIFADAIFPCSELLAELFNIPFVYSLSFSPGYTF
EKHSGGFIFPPSYVPVVMSELTDQMTFMERVKNMIYVLYFDFWFEIFDMKKWDQFYSEVL
GRPTTLSETMGKADVWLIRNSWNFQFPYPLLPNVDFVGGLHCKPAKPLPKEMEDFVQSSG
ENGVVVFSLGSMVSNMTEERANVIASALAQIPQKVLWRFDGNKPDTLGLNTRLYKWIPQN
DLLGHPKTRAFITHGGANGIYEAIYHGIPMVGIPLFADQPDNIAHMKARGAAVRVDFNTM
SSTDLLNALKRVINDPSYKENVMKLSRIQHDQPVKPLDRAVFWIEFVMRHKGAKHLRVAA
HDLTWFQYHSLDVIGFLLVCVATVIFIVTKCCLFCFWKFARKAKKGKND
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| BDBM50211771 |
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| n/a |
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| Name | BDBM50211771 |
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| Synonyms: | CHEMBL226513 | diethyl {(3S)-3-hydroxy-3-[(1R,2S,7S,8S,9S)-3,3,7-trimethyltricyclo[5.4.0.02,9]undec-8-yl]propyl}phosphonate |
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| Type | Small organic molecule |
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| Emp. Form. | C21H39O4P |
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| Mol. Mass. | 386.5057 |
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| SMILES | CCOP(=O)(CC[C@H](O)[C@H]1[C@H]2CC[C@@H]3[C@@H]2C(C)(C)CCC[C@]13C)OCC |TLB:7:9:11.12:14,THB:20:21:11.12:14,15:14:11.12:9.21,22:21:11.12:14| |
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| Structure | 
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