| Reaction Details |
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 | Report a problem with these data |
| Target | Apoptosis regulator Bcl-2 |
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| Ligand | BDBM50202270 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_441637 (CHEMBL891868) |
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| Ki | >1000000±n/a nM |
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| Citation |  Xing, C; Wang, L; Tang, X; Sham, YY Development of selective inhibitors for anti-apoptotic Bcl-2 proteins from BHI-1. Bioorg Med Chem15:2167-76 (2007) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Apoptosis regulator Bcl-2 |
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| Name: | Apoptosis regulator Bcl-2 |
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| Synonyms: | Apoptosis regulator Bcl-2 Protein | B-cell lymphoma 2 protein (Bcl-2) | BCL-2 | BCL2 | BCL2_HUMAN | Bcl-2 Protein |
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| Type: | Homodimer or heterodimer |
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| Mol. Mass.: | 26269.11 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P10415 |
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| Residue: | 239 |
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| Sequence: | MAHAGRTGYDNREIVMKYIHYKLSQRGYEWDAGDVGAAPPGAAPAPGIFSSQPGHTPHPA
ASRDPVARTSPLQTPAAPGAAAGPALSPVPPVVHLTLRQAGDDFSRRYRRDFAEMSSQLH
LTPFTARGRFATVVEELFRDGVNWGRIVAFFEFGGVMCVESVNREMSPLVDNIALWMTEY
LNRHLHTWIQDNGGWDAFVELYGPSMRPLFDFSWLSLKTLLSLALVGACITLGAYLGHK
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| BDBM50202270 |
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| n/a |
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| Name | BDBM50202270 |
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| Synonyms: | 2-propenyl 2-[5-(4-bromobenzylidene)-4-oxo-2-thioxothiazolidin-3-yl]-3-phenylpropanoate | CHEMBL243411 |
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| Type | Small organic molecule |
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| Emp. Form. | C22H18BrNO3S2 |
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| Mol. Mass. | 488.417 |
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| SMILES | Brc1ccc(\C=C2/SC(=S)N([C@@H](Cc3ccccc3)C(=O)OCC=C)C2=O)cc1 |
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| Structure | 
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