| Reaction Details |
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 | Report a problem with these data |
| Target | Sigma non-opioid intracellular receptor 1 |
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| Ligand | BDBM50219752 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_445893 (CHEMBL896183) |
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| Ki | 2020±n/a nM |
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| Citation |  Ferorelli, S; Abate, C; Colabufo, NA; Niso, M; Inglese, C; Berardi, F; Perrone, R Design and evaluation of naphthol- and carbazole-containing fluorescent sigma ligands as potential probes for receptor binding studies. J Med Chem50:4648-55 (2007) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Sigma non-opioid intracellular receptor 1 |
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| Name: | Sigma non-opioid intracellular receptor 1 |
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| Synonyms: | OPRS1 | SGMR1_CAVPO | SIGMAR1 | Sigma 1-type opioid receptor | Sigma non-opioid intracellular receptor 1 | Sigma-1 receptor | Sigma1-receptor | Sigma1R | Sterol isomerase-like protein |
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| Type: | Protein |
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| Mol. Mass.: | 25307.17 |
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| Organism: | Cavia porcellus (Guinea pig) |
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| Description: | Q60492 |
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| Residue: | 223 |
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| Sequence: | MQWAVGRRWLWVALFLAAVAVLTQIVWLWLGTQNFVFQREEIAQLARQYAGLDHELAFSK
LIVELRRLHPVHVLPDEELQWVFVNAGGWMGAMCLLHASLSEYVLLFGTALGSPRHSGRY
WAEISDTIISGTFHQWREGTTKSEVFYPGETVVHGPGEATAVEWGPNTWMVEYGRGVIPS
TLGFALADTVFSTQDFLTLFYTLRVYARALQLELTTYLFGQDP
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| BDBM50219752 |
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| n/a |
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| Name | BDBM50219752 |
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| Synonyms: | 3,3-dimethyl-1-[3-(9H-carbazol-9-yl)propyl]piperidine hydrochloride | CHEMBL536759 |
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| Type | Small organic molecule |
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| Emp. Form. | C22H28N2 |
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| Mol. Mass. | 320.4711 |
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| SMILES | CC1(C)CCCN(CCCn2c3ccccc3c3ccccc23)C1 |
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| Structure | 
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