| Reaction Details |
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 | Report a problem with these data |
| Target | D(1A) dopamine receptor |
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| Ligand | BDBM50373494 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_467933 (CHEMBL951042) |
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| Ki | 3900±n/a nM |
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| Citation |  Prante, O; Tietze, R; Hocke, C; Löber, S; Hübner, H; Kuwert, T; Gmeiner, P Synthesis, radiofluorination, and in vitro evaluation of pyrazolo[1,5-a]pyridine-based dopamine D4 receptor ligands: discovery of an inverse agonist radioligand for PET. J Med Chem51:1800-10 (2008) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| D(1A) dopamine receptor |
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| Name: | D(1A) dopamine receptor |
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| Synonyms: | DRD1 | DRD1_PIG | Dopamine D1 receptor |
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| Type: | PROTEIN |
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| Mol. Mass.: | 49269.92 |
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| Organism: | Sus scrofa |
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| Description: | ChEMBL_1460140 |
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| Residue: | 446 |
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| Sequence: | MRTLNTSTMDGTGLVVERDFSFRILTACFLSLLILSTLLGNTLVCAAVIRFRHLRSKVTN
FFVISLAVSDLLVAVLVMPWKAVAEIAGFWPFGSFCNIWVAFDIMCSTASILNLCVISVD
RYWAISSPFRYERKMTPKAAFILISVAWTLSVLISFIPVQLSWHKAKPTSPSDGNVTSLG
KTTHNCDSSLSRTYAISSSLISFYIPVAIMIVTYTRIYRIAQKQIRRISALERAAVHAKN
CQTTAGNGNPAECSQPESSFKMSFKRETKVLKTLSVIMGVFVCCWLPFFILNCMVPFCGS
GETKPFCIDSITFDVFVWFGWANSSLNPIIYAFNADFRKAFSTLLGCYRLCPTSTNAIET
VSINNNGAVVFSSHHEPRGSISKDCNLVYLIPHAVGSSEDLKKEEAGGIASPLEKLSPAL
SVILDYDTDVSLEKIQPITQNGQHPT
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| BDBM50373494 |
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| n/a |
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| Name | BDBM50373494 |
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| Synonyms: | CHEMBL272395 |
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| Type | Small organic molecule |
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| Emp. Form. | C17H18BrN5 |
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| Mol. Mass. | 372.262 |
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| SMILES | Brc1cccc(n1)N1CCN(Cc2cnn3ccccc23)CC1 |
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| Structure | 
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