| Reaction Details |
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 | Report a problem with these data |
| Target | Adenosine receptor A2a |
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| Ligand | BDBM50375497 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_472689 (CHEMBL922856) |
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| Ki | 48.2±n/a nM |
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| Citation |  van Veldhoven, JP; Chang, LC; von Frijtag Drabbe Künzel, JK; Mulder-Krieger, T; Struensee-Link, R; Beukers, MW; Brussee, J; IJzerman, AP A new generation of adenosine receptor antagonists: from di- to trisubstituted aminopyrimidines. Bioorg Med Chem16:2741-52 (2008) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Adenosine receptor A2a |
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| Name: | Adenosine receptor A2a |
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| Synonyms: | A2A adenosine receptor (hA2A) | AA2AR_HUMAN | ADENOSINE A2 | ADENOSINE A2a | ADORA2 | ADORA2A | Adenosine A2A receptor (A2AAR) |
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| Type: | G Protein-Coupled Receptor (GPCR) |
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| Mol. Mass.: | 44716.46 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P29274 |
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| Residue: | 412 |
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| Sequence: | MPIMGSSVYITVELAIAVLAILGNVLVCWAVWLNSNLQNVTNYFVVSLAAADIAVGVLAI
PFAITISTGFCAACHGCLFIACFVLVLTQSSIFSLLAIAIDRYIAIRIPLRYNGLVTGTR
AKGIIAICWVLSFAIGLTPMLGWNNCGQPKEGKNHSQGCGEGQVACLFEDVVPMNYMVYF
NFFACVLVPLLLMLGVYLRIFLAARRQLKQMESQPLPGERARSTLQKEVHAAKSLAIIVG
LFALCWLPLHIINCFTFFCPDCSHAPLWLMYLAIVLSHTNSVVNPFIYAYRIREFRQTFR
KIIRSHVLRQQEPFKAAGTSARVLAAHGSDGEQVSLRLNGHPPGVWANGSAPHPERRPNG
YALGLVSGGSAQESQGNTGLPDVELLSHELKGVCPEPPGLDDPLAQDGAGVS
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| BDBM50375497 |
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| n/a |
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| Name | BDBM50375497 |
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| Synonyms: | CHEMBL259075 |
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| Type | Small organic molecule |
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| Emp. Form. | C21H18N4O |
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| Mol. Mass. | 342.3938 |
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| SMILES | CCCC(=O)Nc1nc(-c2ccccc2)c(C#N)c(n1)-c1ccccc1 |
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| Structure | 
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