| Reaction Details |
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 | Report a problem with these data |
| Target | Cathepsin S |
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| Ligand | BDBM50376508 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_477023 (CHEMBL933741) |
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| IC50 | >1000±n/a nM |
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| Citation |  Teno, N; Irie, O; Miyake, T; Gohda, K; Horiuchi, M; Tada, S; Nonomura, K; Kometani, M; Iwasaki, G; Betschart, C New chemotypes for cathepsin K inhibitors. Bioorg Med Chem Lett18:2599-603 (2008) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Cathepsin S |
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| Name: | Cathepsin S |
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| Synonyms: | CATS_HUMAN | CTSS | Cathepsin S (Cat S) | cathepsin S preproprotein |
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| Type: | Protein |
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| Mol. Mass.: | 37507.38 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P25774 |
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| Residue: | 331 |
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| Sequence: | MKRLVCVLLVCSSAVAQLHKDPTLDHHWHLWKKTYGKQYKEKNEEAVRRLIWEKNLKFVM
LHNLEHSMGMHSYDLGMNHLGDMTSEEVMSLMSSLRVPSQWQRNITYKSNPNRILPDSVD
WREKGCVTEVKYQGSCGACWAFSAVGALEAQLKLKTGKLVSLSAQNLVDCSTEKYGNKGC
NGGFMTTAFQYIIDNKGIDSDASYPYKAMDQKCQYDSKYRAATCSKYTELPYGREDVLKE
AVANKGPVSVGVDARHPSFFLYRSGVYYEPSCTQNVNHGVLVVGYGDLNGKEYWLVKNSW
GHNFGEEGYIRMARNKGNHCGIASFPSYPEI
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| BDBM50376508 |
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| n/a |
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| Name | BDBM50376508 |
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| Synonyms: | CHEMBL261455 |
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| Type | Small organic molecule |
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| Emp. Form. | C24H30N6O3S |
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| Mol. Mass. | 482.598 |
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| SMILES | COc1ccc(cc1)S(=O)(=O)N1CCN(CC#Cc2cnc(nc2NCC(C)(C)C)C#N)CC1 |
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| Structure | 
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