| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Somatostatin receptor type 4 |
|---|
| Ligand | BDBM50254251 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_560341 (CHEMBL1009181) |
|---|
| IC50 | 2.1±n/a nM |
|---|
| Citation |  Feytens, D; De Vlaeminck, M; Cescato, R; Tourwé, D; Reubi, JC Highly potent 4-amino-indolo[2,3-c]azepin-3-one-containing somatostatin mimetics with a range of sst receptor selectivities. J Med Chem52:95-104 (2009) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Somatostatin receptor type 4 |
|---|
| Name: | Somatostatin receptor type 4 |
|---|
| Synonyms: | SOMATOSTATIN SST4 | SS-4-R | SS4-R | SS4R | SSR4_HUMAN | SST4R | SSTR4 | Somatostatin receptor type 4 (SSTR4) |
|---|
| Type: | Enzyme |
|---|
| Mol. Mass.: | 42015.38 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | P31391 |
|---|
| Residue: | 388 |
|---|
| Sequence: | MSAPSTLPPGGEEGLGTAWPSAANASSAPAEAEEAVAGPGDARAAGMVAIQCIYALVCLV
GLVGNALVIFVILRYAKMKTATNIYLLNLAVADELFMLSVPFVASSAALRHWPFGSVLCR
AVLSVDGLNMFTSVFCLTVLSVDRYVAVVHPLRAATYRRPSVAKLINLGVWLASLLVTLP
IAIFADTRPARGGQAVACNLQWPHPAWSAVFVVYTFLLGFLLPVLAIGLCYLLIVGKMRA
VALRAGWQQRRRSEKKITRLVLMVVVVFVLCWMPFYVVQLLNLFVTSLDATVNHVSLILS
YANSCANPILYGFLSDNFRRFFQRVLCLRCCLLEGAGGAEEEPLDYYATALKSKGGAGCM
CPPLPCQQEALQPEPGRKRIPLTRTTTF
|
|
|
|---|
| BDBM50254251 |
|---|
| n/a |
|---|
| Name | BDBM50254251 |
|---|
| Synonyms: | (5S)-6-(benzylamino)-5-((4R)-4-(1-(methylsulfonyl)spiro[indoline-3,4'-piperidine]-1'-ylcarboxamido)-3-oxo-4,5-dihydroazepino[3,4-b]indol-2(1H,3H,10H)-yl)-6-oxohexan-1-aminium trifluoroacetate | CHEMBL503379 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C39H47N7O5S |
|---|
| Mol. Mass. | 725.899 |
|---|
| SMILES | CS(=O)(=O)N1CC2(CCN(CC2)C(=O)N[C@@H]2Cc3c(CN([C@@H](CCCCN)C(=O)NCc4ccccc4)C2=O)[nH]c2ccccc32)c2ccccc12 |r| |
|---|
| Structure | 
|
|---|
Search and Browse
