Reaction Details | |||
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Target | Sigma non-opioid intracellular receptor 1 | ||
Ligand | BDBM50274971 | ||
Substrate/Competitor | n/a | ||
Meas. Tech. | ChEMBL_496151 (CHEMBL1000140) | ||
Ki | 6.3±n/a nM | ||
Citation | ![]() | ||
More Info.: | Get all data from this article, Assay Method | ||
Sigma non-opioid intracellular receptor 1 | |||
Name: | Sigma non-opioid intracellular receptor 1 | ||
Synonyms: | OPRS1 | SGMR1_CAVPO | SIGMAR1 | Sigma 1-type opioid receptor | Sigma non-opioid intracellular receptor 1 | Sigma-1 receptor | Sigma1-receptor | Sigma1R | Sterol isomerase-like protein | ||
Type: | Protein | ||
Mol. Mass.: | 25307.17 | ||
Organism: | Cavia porcellus (Guinea pig) | ||
Description: | Q60492 | ||
Residue: | 223 | ||
Sequence: |
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BDBM50274971 | |||
n/a | |||
Name | BDBM50274971 | ||
Synonyms: | CHEMBL511680 | cis-4-[4-(2,6-Dimethylyphenyl)cyclohexyl]-1-(2-pyridinyl)piperazine | ||
Type | Small organic molecule | ||
Emp. Form. | C23H31N3 | ||
Mol. Mass. | 349.5123 | ||
SMILES | Cc1cccc(C)c1[C@@H]1CC[C@@H](CC1)N1CCN(CC1)c1ccccn1 |r,wU:11.15,8.8,(4.14,-25.41,;4.15,-26.95,;2.82,-27.72,;2.82,-29.27,;4.15,-30.04,;5.49,-29.26,;6.82,-30.03,;5.48,-27.71,;6.81,-26.93,;8.15,-27.7,;9.47,-26.93,;9.48,-25.39,;8.14,-24.62,;6.8,-25.4,;10.8,-24.62,;12.14,-25.4,;13.46,-24.63,;13.47,-23.1,;12.14,-22.32,;10.8,-23.09,;14.81,-22.33,;14.81,-20.8,;16.14,-20.03,;17.48,-20.8,;17.47,-22.34,;16.13,-23.11,)| | ||
Structure | ![]() |