| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Neprilysin [1-24] |
|---|
| Ligand | BDBM50298111 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_585130 (CHEMBL1060019) |
|---|
| IC50 | 430±n/a nM |
|---|
| Citation |  Olimpieri, F; Tambaro, S; Fustero, S; Lazzari, P; Sanchez-Roselló, M; Pani, L; Volonterio, A; Zanda, M Synthesis and enzymatic evaluation of novel partially fluorinated thiol dual ACE/NEP inhibitors. Bioorg Med Chem Lett19:4715-9 (2009) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Neprilysin [1-24] |
|---|
| Name: | Neprilysin [1-24] |
|---|
| Synonyms: | MME | NEP_PIG | Neprilysin |
|---|
| Type: | PROTEIN |
|---|
| Mol. Mass.: | 2817.48 |
|---|
| Organism: | Sus scrofa |
|---|
| Description: | ChEMBL_585130 |
|---|
| Residue: | 24 |
|---|
| Sequence: | |
|---|
| BDBM50298111 |
|---|
| n/a |
|---|
| Name | BDBM50298111 |
|---|
| Synonyms: | 3-(4-Hydroxy-phenyl)-2-[3-phenyl-2-(4,4,4-trifluoro-3-mercapto-butyrylamino)-propionylamino]-propionic acid | CHEMBL560409 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C22H23F3N2O5S |
|---|
| Mol. Mass. | 484.489 |
|---|
| SMILES | OC(=O)C(Cc1ccc(O)cc1)NC(=O)C(Cc1ccccc1)NC(=O)CC(S)C(F)(F)F |
|---|
| Structure | 
|
|---|
Search and Browse
