| Reaction Details |
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 | Report a problem with these data |
| Target | Carbonic anhydrase |
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| Ligand | BDBM10885 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_587743 (CHEMBL1038579) |
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| Ki | 48.2±n/a nM |
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| Citation |  Bertucci, A; Innocenti, A; Zoccola, D; Scozzafava, A; Tambutté, S; Supuran, CT Carbonic anhydrase inhibitors. Inhibition studies of a coral secretory isoform by sulfonamides. Bioorg Med Chem17:5054-8 (2009) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Carbonic anhydrase |
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| Name: | Carbonic anhydrase |
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| Synonyms: | Alpha carbonic anhydrase |
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| Type: | PROTEIN |
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| Mol. Mass.: | 36650.57 |
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| Organism: | Stylophora pistillata |
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| Description: | ChEMBL_700658 |
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| Residue: | 323 |
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| Sequence: | MKLSLFISSLLAMIVACPNLAESAGSWTYRDPEGPDTWKHHYKDCEGHEQSPINIVPKDT
FFEPGLADLVVNYEKSVSAKLFNNGHTVQATFLTGKSNISGGNLTSHFRALQMHFHWGSE
NSRGSEHQVGGRKFPLEIHIVHYNAEKYPSVSEAVDKGDGLAVLGILVELQVQDNPVFDV
MVDNLDKARYKGNEVILPSLQPFSFLPHDIAQYYTYRGSLTTPGCFESVQWFVFNHTFPI
SQAQLDKFRDLFDSEKQDTKKLPLVDNYRPVQPLYGRSVSEASNALLFPVARHQTKLWIA
WDSLMTRQYFMKQQSICALYQPQ
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| BDBM10885 |
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| n/a |
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| Name | BDBM10885 |
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| Synonyms: | (4R)-4-(ethylamino)-2-(3-methoxypropyl)-1,1-dioxo-2H,3H,4H-1,7,2-thieno[3,2-e][1,2]thiazine-6-sulfonamide | (R)-4-(ethylamino)-3,4-dihydro-2-(3-methoxypropyl)-2H-thieno(3,2-E)-1,2-thiazine-6-sulfonamide 1,1-dioxide | AL-4862 | Azopt | Brinzolamide (BRZ) | brinzolamide |
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| Type | Small organic molecule |
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| Emp. Form. | C12H21N3O5S3 |
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| Mol. Mass. | 383.507 |
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| SMILES | CCN[C@H]1CN(CCCOC)S(=O)(=O)c2sc(cc12)S(N)(=O)=O |r| |
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| Structure | 
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