| Reaction Details |
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 | Report a problem with these data |
| Target | Neuronal acetylcholine receptor subunit alpha-7 |
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| Ligand | BDBM50321022 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_639431 (CHEMBL1168404) |
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| Ki | >100000±n/a nM |
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| Citation |  Dallanoce, C; Frigerio, F; Martelli, G; Grazioso, G; Matera, C; Pomè, DY; Pucci, L; Clementi, F; Gotti, C; De Amici, M Novel tricyclic Delta(2)-isoxazoline and 3-oxo-2-methyl-isoxazolidine derivatives: synthesis and binding affinity at neuronal nicotinic acetylcholine receptor subtypes. Bioorg Med Chem18:4498-508 (2010) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Neuronal acetylcholine receptor subunit alpha-7 |
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| Name: | Neuronal acetylcholine receptor subunit alpha-7 |
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| Synonyms: | ACHA7_RAT | Acra7 | Cholinergic, Nicotinic Alpha7 | Cholinergic, Nicotinic Alpha7/5-HT3 | Chrna7 | Neuronal acetylcholine receptor | Neuronal acetylcholine receptor (alpha7 nAChR) | Neuronal acetylcholine receptor subunit alpha 7 | Neuronal acetylcholine receptor subunit alpha-7 | Neuronal acetylcholine receptor subunit alpha-7 (nAChR alpha7) | Neuronal acetylcholine receptor subunit alpha-7 (nAChR) |
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| Type: | Enzyme |
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| Mol. Mass.: | 56502.44 |
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| Organism: | Rattus norvegicus (Rat) |
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| Description: | Q05941 |
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| Residue: | 502 |
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| Sequence: | MCGGRGGIWLALAAALLHVSLQGEFQRRLYKELVKNYNPLERPVANDSQPLTVYFSLSLL
QIMDVDEKNQVLTTNIWLQMSWTDHYLQWNMSEYPGVKNVRFPDGQIWKPDILLYNSADE
RFDATFHTNVLVNASGHCQYLPPGIFKSSCYIDVRWFPFDVQQCKLKFGSWSYGGWSLDL
QMQEADISSYIPNGEWDLMGIPGKRNEKFYECCKEPYPDVTYTVTMRRRTLYYGLNLLIP
CVLISALALLVFLLPADSGEKISLGITVLLSLTVFMLLVAEIMPATSDSVPLIAQYFAST
MIIVGLSVVVTVIVLRYHHHDPDGGKMPKWTRIILLNWCAWFLRMKRPGEDKVRPACQHK
PRRCSLASVELSAGAGPPTSNGNLLYIGFRGLEGMHCAPTPDSGVVCGRLACSPTHDEHL
MHGAHPSDGDPDLAKILEEVRYIANRFRCQDESEVICSEWKFAACVVDRLCLMAFSVFTI
ICTIGILMSAPNFVEAVSKDFA
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| BDBM50321022 |
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| n/a |
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| Name | BDBM50321022 |
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| Synonyms: | 4-Methyl-3-oxa-4,11-diazatricyclo[6.2.1.0'2,6]undecan-5-one fumaric acid | CHEMBL1164459 |
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| Type | Small organic molecule |
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| Emp. Form. | C9H14N2O2 |
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| Mol. Mass. | 182.2197 |
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| SMILES | CN1OC2C3CCC(CC2C1=O)N3 |THB:10:9:5.6:12,2:3:5.6:12| |
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| Structure | 
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