| Reaction Details |
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 | Report a problem with these data |
| Target | Sigma non-opioid intracellular receptor 1 |
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| Ligand | BDBM50322246 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_642593 (CHEMBL1176482) |
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| Ki | 15.1±n/a nM |
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| Citation |  Vangveravong, S; Taylor, M; Xu, J; Cui, J; Calvin, W; Babic, S; Luedtke, RR; Mach, RH Synthesis and characterization of selective dopamine D2 receptor antagonists. 2. Azaindole, benzofuran, and benzothiophene analogs of L-741,626. Bioorg Med Chem18:5291-300 (2010) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Sigma non-opioid intracellular receptor 1 |
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| Name: | Sigma non-opioid intracellular receptor 1 |
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| Synonyms: | OPRS1 | SGMR1_CAVPO | SIGMAR1 | Sigma 1-type opioid receptor | Sigma non-opioid intracellular receptor 1 | Sigma-1 receptor | Sigma1-receptor | Sigma1R | Sterol isomerase-like protein |
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| Type: | Protein |
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| Mol. Mass.: | 25307.17 |
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| Organism: | Cavia porcellus (Guinea pig) |
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| Description: | Q60492 |
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| Residue: | 223 |
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| Sequence: | MQWAVGRRWLWVALFLAAVAVLTQIVWLWLGTQNFVFQREEIAQLARQYAGLDHELAFSK
LIVELRRLHPVHVLPDEELQWVFVNAGGWMGAMCLLHASLSEYVLLFGTALGSPRHSGRY
WAEISDTIISGTFHQWREGTTKSEVFYPGETVVHGPGEATAVEWGPNTWMVEYGRGVIPS
TLGFALADTVFSTQDFLTLFYTLRVYARALQLELTTYLFGQDP
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| BDBM50322246 |
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| n/a |
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| Name | BDBM50322246 |
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| Synonyms: | 1-((1H-Pyrrolo[2,3-b]pyridine-3-yl)methyl)-4-(4-bromophenyl)piperidin-4-ol oxalate | CHEMBL1170879 |
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| Type | Small organic molecule |
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| Emp. Form. | C19H20BrN3O |
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| Mol. Mass. | 386.286 |
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| SMILES | OC1(CCN(Cc2c[nH]c3ncccc23)CC1)c1ccc(Br)cc1 |
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| Structure | 
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