| Reaction Details |
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 | Report a problem with these data |
| Target | Amine oxidase [flavin-containing] B |
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| Ligand | BDBM50327221 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_664237 (CHEMBL1261744) |
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| IC50 | 86000±n/a nM |
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| Citation |  Khattab, SN; Hassan, SY; Bekhit, AA; El Massry, AM; Langer, V; Amer, A Synthesis of new series of quinoxaline based MAO-inhibitors and docking studies. Eur J Med Chem45:4479-89 (2010) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Amine oxidase [flavin-containing] B |
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| Name: | Amine oxidase [flavin-containing] B |
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| Synonyms: | AOFB_HUMAN | MAO-B | MAOB | Monoamine oxidase type B | Monoamine oxidase type B (MAO B) | Monoamine oxidase type B (MAO B) | Monoamine oxidase type B (MAOB) |
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| Type: | Protein |
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| Mol. Mass.: | 58768.76 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P27338 |
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| Residue: | 520 |
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| Sequence: | MSNKCDVVVVGGGISGMAAAKLLHDSGLNVVVLEARDRVGGRTYTLRNQKVKYVDLGGSY
VGPTQNRILRLAKELGLETYKVNEVERLIHHVKGKSYPFRGPFPPVWNPITYLDHNNFWR
TMDDMGREIPSDAPWKAPLAEEWDNMTMKELLDKLCWTESAKQLATLFVNLCVTAETHEV
SALWFLWYVKQCGGTTRIISTTNGGQERKFVGGSGQVSERIMDLLGDRVKLERPVIYIDQ
TRENVLVETLNHEMYEAKYVISAIPPTLGMKIHFNPPLPMMRNQMITRVPLGSVIKCIVY
YKEPFWRKKDYCGTMIIDGEEAPVAYTLDDTKPEGNYAAIMGFILAHKARKLARLTKEER
LKKLCELYAKVLGSLEALEPVHYEEKNWCEEQYSGGCYTTYFPPGILTQYGRVLRQPVDR
IYFAGTETATHWSGYMEGAVEAGERAAREILHAMGKIPEDEIWQSEPESVDVPAQPITTT
FLERHLPSVPGLLRLIGLTTIFSATALGFLAHKRGLLVRV
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| BDBM50327221 |
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| n/a |
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| Name | BDBM50327221 |
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| Synonyms: | 4-Benzoyl-1-(3,4-dimethoxyphenyl)-[1,2,4]triazolo[4,3-a]quinoxaline | CHEMBL1258955 |
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| Type | Small organic molecule |
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| Emp. Form. | C24H18N4O3 |
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| Mol. Mass. | 410.4247 |
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| SMILES | COc1ccc(cc1OC)-c1nnc2c(nc3ccccc3n12)C(=O)c1ccccc1 |
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| Structure | 
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