| Reaction Details |
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 | Report a problem with these data |
| Target | Dual specificity protein kinase CLK1 |
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| Ligand | BDBM50383304 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_819991 (CHEMBL2032666) |
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| IC50 | >10000±n/a nM |
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| Citation |  Nguyen, TB; Lozach, O; Surpateanu, G; Wang, Q; Retailleau, P; Iorga, BI; Meijer, L; Guéritte, F Synthesis, biological evaluation, and molecular modeling of natural and unnatural flavonoidal alkaloids, inhibitors of kinases. J Med Chem55:2811-9 (2012) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Dual specificity protein kinase CLK1 |
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| Name: | Dual specificity protein kinase CLK1 |
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| Synonyms: | CDC-like kinase 1 | CLK1_MOUSE | Clk | Clk1 | Protein kinase STY | Sty |
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| Type: | PROTEIN |
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| Mol. Mass.: | 57124.52 |
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| Organism: | Mus musculus |
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| Description: | ChEMBL_1502245 |
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| Residue: | 483 |
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| Sequence: | MRHSKRTYCPDWDERDWDYGTWRSSSSHKRKKRSHSSAREQKRCRYDHSKTTDSYYLESR
SINEKAYHSRRYVDEYRNDYMGYEPGHPYGEPGSRYQMHSSKSSGRSGRSSYKSKHRSRH
HTSQHHSHGKSHRRKRSRSVEDDEEGHLICQSGDVLSARYEIVDTLGEGAFGKVVECIDH
KVGGRRVAVKIVKNVDRYCEAAQSEIQVLEHLNTTDPHSTFRCVQMLEWFEHRGHICIVF
ELLGLSTYDFIKENSFLPFRMDHIRKMAYQICKSVNFLHSNKLTHTDLKPENILFVKSDY
TEAYNPKMKRDERTIVNPDIKVVDFGSATYDDEHHSTLVSTRHYRAPEVILALGWSQPCD
VWSIGCILIEYYLGFTVFPTHDSREHLAMMERILGPLPKHMIQKTRKRRYFHHDRLDWDE
HSSAGRYVSRRCKPLKEFMLSQDAEHELLFDLIGKMLEYDPAKRITLKEALKHPFFYPLK
KHT
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| BDBM50383304 |
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| n/a |
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| Name | BDBM50383304 |
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| Synonyms: | CHEMBL2029622 |
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| Type | Small organic molecule |
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| Emp. Form. | C22H25NO4 |
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| Mol. Mass. | 367.4382 |
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| SMILES | CCCCC[C@@H](NC)c1c(O)cc(O)c2c1oc(cc2=O)-c1ccccc1 |r| |
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| Structure | 
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