| Reaction Details |
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 | Report a problem with these data |
| Target | Neuropeptide Y receptor type 2 |
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| Ligand | BDBM42524 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_820067 (CHEMBL2032840) |
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| IC50 | 440±n/a nM |
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| Citation |  Mittapalli, GK; Vellucci, D; Yang, J; Toussaint, M; Brothers, SP; Wahlestedt, C; Roberts, E Synthesis and SAR of selective small molecule neuropeptide Y Y2 receptor antagonists. Bioorg Med Chem Lett22:3916-20 (2012) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Neuropeptide Y receptor type 2 |
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| Name: | Neuropeptide Y receptor type 2 |
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| Synonyms: | NPY-Y2 | NPY-Y2 receptor | NPY2-R | NPY2R | NPY2R_HUMAN | Neuropeptide Y receptor type 2 | Y2 receptor | neuropeptide Y receptor Y2 |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 42734.65 |
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| Organism: | Homo sapiens (Human) |
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| Description: | NPY-Y2 NPY2R HUMAN::P49146 |
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| Residue: | 381 |
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| Sequence: | MGPIGAEADENQTVEEMKVEQYGPQTTPRGELVPDPEPELIDSTKLIEVQVVLILAYCSI
ILLGVIGNSLVIHVVIKFKSMRTVTNFFIANLAVADLLVNTLCLPFTLTYTLMGEWKMGP
VLCHLVPYAQGLAVQVSTITLTVIALDRHRCIVYHLESKISKRISFLIIGLAWGISALLA
SPLAIFREYSLIEIIPDFEIVACTEKWPGEEKSIYGTVYSLSSLLILYVLPLGIISFSYT
RIWSKLKNHVSPGAANDHYHQRRQKTTKMLVCVVVVFAVSWLPLHAFQLAVDIDSQVLDL
KEYKLIFTVFHIIAMCSTFANPLLYGWMNSNYRKAFLSAFRCEQRLDAIHSEVSVTFKAK
KNLEVRKNSGPNDSFTEATNV
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| BDBM42524 |
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| n/a |
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| Name | BDBM42524 |
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| Synonyms: | 3-[(2,5-dimethylphenyl)sulfamoyl]-4-methyl-N-(2-phenylphenyl)benzamide | MLS000582311 | N-2-biphenylyl-3-{[(2,5-dimethylphenyl)amino]sulfonyl}-4-methylbenzamide | SMR000200850 | cid_2223246 |
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| Type | Small organic molecule |
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| Emp. Form. | C28H26N2O3S |
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| Mol. Mass. | 470.583 |
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| SMILES | Cc1ccc(C)c(NS(=O)(=O)c2cc(ccc2C)C(=O)Nc2ccccc2-c2ccccc2)c1 |
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| Structure | 
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