| Reaction Details |
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 | Report a problem with these data |
| Target | Mitogen-activated protein kinase 13 |
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| Ligand | BDBM50389320 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_831788 (CHEMBL2065151) |
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| IC50 | <10000±n/a nM |
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| Citation |  Maryanoff, BE; O'Neill, JC; McComsey, DF; Yabut, SC; Luci, DK; Gibbs, AC; Connelly, MA Pyrimidinopyrimidine inhibitors of ketohexokinase: exploring the ring C2 group that interacts with Asp-27B in the ligand binding pocket. Bioorg Med Chem Lett22:5326-9 (2012) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Mitogen-activated protein kinase 13 |
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| Name: | Mitogen-activated protein kinase 13 |
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| Synonyms: | MAP kinase p38 delta | MAPK13 | MK13_HUMAN | Mitogen-activated protein kinase 13 | Mitogen-activated protein kinase 13 (MAPK13) | Mitogen-activated protein kinase p38 | Mitogen-activated protein kinase p38 delta | PRKM13 | SAPK4 | Stress-activated protein kinase 4 | p38 delta/gamma |
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| Type: | Enzyme |
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| Mol. Mass.: | 42097.16 |
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| Organism: | Homo sapiens (Human) |
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| Description: | O15264 |
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| Residue: | 365 |
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| Sequence: | MSLIRKKGFYKQDVNKTAWELPKTYVSPTHVGSGAYGSVCSAIDKRSGEKVAIKKLSRPF
QSEIFAKRAYRELLLLKHMQHENVIGLLDVFTPASSLRNFYDFYLVMPFMQTDLQKIMGM
EFSEEKIQYLVYQMLKGLKYIHSAGVVHRDLKPGNLAVNEDCELKILDFGLARHADAEMT
GYVVTRWYRAPEVILSWMHYNQTVDIWSVGCIMAEMLTGKTLFKGKDYLDQLTQILKVTG
VPGTEFVQKLNDKAAKSYIQSLPQTPRKDFTQLFPRASPQAADLLEKMLELDVDKRLTAA
QALTHPFFEPFRDPEEETEAQQPFDDSLEHEKLTVDEWKQHIYKEIVNFSPIARKDSRRR
SGMKL
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| BDBM50389320 |
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| n/a |
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| Name | BDBM50389320 |
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| Synonyms: | CHEMBL2063926 |
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| Type | Small organic molecule |
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| Emp. Form. | C26H35N9S |
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| Mol. Mass. | 505.681 |
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| SMILES | CSc1ccccc1Nc1nc(nc2c(NCC3CC3)ncnc12)N1CCN(CC1)C1CCNCC1 |
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| Structure | 
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