| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Prostaglandin E synthase |
|---|
| Ligand | BDBM50391887 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_849365 (CHEMBL2149157) |
|---|
| IC50 | 5300±n/a nM |
|---|
| Citation |  Baumgartner, L; Sosa, S; Atanasov, AG; Bodensieck, A; Fakhrudin, N; Bauer, J; Favero, GD; Ponti, C; Heiss, EH; Schwaiger, S; Ladurner, A; Widowitz, U; Loggia, RD; Rollinger, JM; Werz, O; Bauer, R; Dirsch, VM; Tubaro, A; Stuppner, H Lignan derivatives from Krameria lappacea roots inhibit acute inflammation in vivo and pro-inflammatory mediators in vitro. J Nat Prod74:1779-86 (2011) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Prostaglandin E synthase |
|---|
| Name: | Prostaglandin E synthase |
|---|
| Synonyms: | MGST1L1 | MPGES1 | PGES | PIG12 | PTGES | PTGES_HUMAN | Prostaglandin E synthase (PGES-1) | Prostaglandin E synthase 1 (mPGES-1) | Prostaglandin E synthase-1 (PGES-1) | Prostaglandin E synthase/G/H synthase 2 | Prostaglandin E2 synthase-1 ( mPGES-1) |
|---|
| Type: | Protein |
|---|
| Mol. Mass.: | 17112.22 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | n/a |
|---|
| Residue: | 152 |
|---|
| Sequence: | MPAHSLVMSSPALPAFLLCSTLLVIKMYVVAIITGQVRLRKKAFANPEDALRHGGPQYCR
SDPDVERCLRAHRNDMETIYPFLFLGFVYSFLGPNPFVAWMHFLVFLVGRVAHTVAYLGK
LRAPIRSVTYTLAQLPCASMALQILWEAARHL
|
|
|
|---|
| BDBM50391887 |
|---|
| n/a |
|---|
| Name | BDBM50391887 |
|---|
| Synonyms: | CHEMBL2147422 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C17H14O2 |
|---|
| Mol. Mass. | 250.2919 |
|---|
| SMILES | C\C=C\c1ccc2oc(cc2c1)-c1ccc(O)cc1 |
|---|
| Structure | 
|
|---|
Search and Browse
