| Reaction Details |
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 | Report a problem with these data |
| Target | Topoisomerase I subunit B |
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| Ligand | BDBM50392268 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_851293 (CHEMBL2155879) |
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| EC50 | 67800±n/a nM |
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| Citation |  Carballeira, NM; Cartagena, M; Sanabria, D; Tasdemir, D; Prada, CF; Reguera, RM; Balaña-Fouce, R 2-Alkynoic fatty acids inhibit topoisomerase IB from Leishmania donovani. Bioorg Med Chem Lett22:6185-9 (2012) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Topoisomerase I subunit B |
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| Name: | Topoisomerase I subunit B |
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| Synonyms: | DNA topoisomerase type IB small subunit | Top1B | Topoisomerase I subunit B |
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| Type: | PROTEIN |
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| Mol. Mass.: | 28099.86 |
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| Organism: | Leishmania major |
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| Description: | ChEMBL_851293 |
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| Residue: | 262 |
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| Sequence: | MQPAQSPPVAPPSVPAAAPKKTPIDISALKLKMSPSVRATLAAAGVLGQCPRPIEAADED
ALLKLKPMKAMAPPVKKAVAPVATTAPPPKVRRVESSSSSSSGSSSSSSDDDSSRDDSSD
SDSSSYSSDDRSSSSAESVVSGEATLFHIAQSQGLVNKEILTQEEEEVPTLVPPRPPVVR
SFPNDIGKALERYRERLNREENIIRIKDDNKAVSLGTSKINYIDPRIICSWAKAQDVPIN
KIFSATIQKKFPWAMNAENFDF
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| BDBM50392268 |
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| n/a |
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| Name | BDBM50392268 |
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| Synonyms: | CHEMBL2153501 |
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| Type | Small organic molecule |
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| Emp. Form. | C14H24O2 |
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| Mol. Mass. | 224.3392 |
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| SMILES | CCCCCCCCCCCC#CC(O)=O |
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| Structure | 
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