| Reaction Details |
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 | Report a problem with these data |
| Target | Bifunctional epoxide hydrolase 2 |
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| Ligand | BDBM25737 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_861581 (CHEMBL2174522) |
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| IC50 | 11±n/a nM |
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| Citation |  Liu, J; Obando, D; Liao, V; Lifa, T; Codd, R The many faces of the adamantyl group in drug design. Eur J Med Chem46:1949-63 (2011) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Bifunctional epoxide hydrolase 2 |
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| Name: | Bifunctional epoxide hydrolase 2 |
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| Synonyms: | Ephx2 | Epoxide hydrolase 2 | HYES_RAT |
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| Type: | PROTEIN |
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| Mol. Mass.: | 62337.15 |
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| Organism: | Rattus norvegicus |
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| Description: | ChEMBL_1465995 |
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| Residue: | 554 |
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| Sequence: | MALRVAAFDLDGVLALPSIAGVLRHTEEALALPRDFLLGAFQMKFPEGPTEQLMKGKITF
SQWVPLMDESCRKSSKACGASLPENFSISEIFSQAMAARSINRPMLQAAAALKKKGFTTC
IVTNNWLDDSDKRDILAQMMCELSQHFDFLIESCQVGMIKPEPQIYKFVLDTLKAKPNEV
VFLDDFGSNLKPARDMGMVTILVRDTASALRELEKVTGTQFPEAPLPVPCSPNDVSHGYV
TVKPGIRLHFVEMGSGPAICLCHGFPESWFSWRYQIPALAQAGFRVLAIDMKGYGDSSSP
PEIEEYAMELLCEEMVTFLNKLGIPQAVFIGHDWAGVLVWNMALFHPERVRAVASLNTPL
MPPNPEVSPMEVIRSIPVFNYQLYFQEPGVAEAELEKNMSRTFKSFFRTSDDMGLLTVNK
ATEMGGILVGTPEDPKVSKITTEEEIEYYIQQFKKSGFRGPLNWYRNTERNWKWSCKALG
RKILVPALMVTAEKDIVLRPEMSKNMENWIPFLKRGHIEDCGHWTQIEKPAEVNQILIKW
LKTEIQNPSVTSKI
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| BDBM25737 |
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| n/a |
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| Name | BDBM25737 |
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| Synonyms: | 12-[(adamantan-1-ylcarbamoyl)amino]dodecanoic acid | CHEMBL215387 | US10383835, Compound 700 | Urea-based compound, 18 |
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| Type | Small organic molecule |
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| Emp. Form. | C23H40N2O3 |
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| Mol. Mass. | 392.5753 |
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| SMILES | OC(=O)CCCCCCCCCCCNC(=O)NC12CC3CC(CC(C3)C1)C2 |TLB:25:20:27:24.23.26,25:24:20.21.19:27,THB:23:22:19:24.25.26,23:24:19:22.21.27| |
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| Structure | 
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