Reaction Details |
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Target | 5-hydroxytryptamine receptor 6 |
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Ligand | BDBM50402713 |
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Substrate/Competitor | n/a |
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Meas. Tech. | ChEMBL_886900 (CHEMBL2211856) |
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Ki | 165±n/a nM |
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Citation | Nirogi, RV; Badange, R; Kambhampati, R; Chindhe, A; Deshpande, AD; Tiriveedhi, V; Kandikere, V; Muddana, N; Abraham, R; Khagga, M Design, synthesis and pharmacological evaluation of 4-(piperazin-1-yl methyl)-N1-arylsulfonyl indole derivatives as 5-HT6 receptor ligands. Bioorg Med Chem Lett22:7431-5 (2012) [PubMed] Article |
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More Info.: | Get all data from this article, Assay Method |
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5-hydroxytryptamine receptor 6 |
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Name: | 5-hydroxytryptamine receptor 6 |
Synonyms: | 5-HT-6 | 5-HT6 | 5-hydroxytryptamine receptor 6 (5-HT-6) | 5-hydroxytryptamine receptor 6 (5-HT6R) | 5-hydroxytryptamine receptor 6 (5HT6) | 5HT6R_HUMAN | HTR6 | Serotonin (5-HT3) receptor | Serotonin 6 (5-HT6) receptor | Serotonin Receptor 6 |
Type: | G Protein-Coupled Receptor (GPCR) |
Mol. Mass.: | 46968.43 |
Organism: | Homo sapiens (Human) |
Description: | P50406 |
Residue: | 440 |
Sequence: | MVPEPGPTANSTPAWGAGPPSAPGGSGWVAAALCVVIALTAAANSLLIALICTQPALRNT
SNFFLVSLFTSDLMVGLVVMPPAMLNALYGRWVLARGLCLLWTAFDVMCCSASILNLCLI
SLDRYLLILSPLRYKLRMTPLRALALVLGAWSLAALASFLPLLLGWHELGHARPPVPGQC
RLLASLPFVLVASGLTFFLPSGAICFTYCRILLAARKQAVQVASLTTGMASQASETLQVP
RTPRPGVESADSRRLATKHSRKALKASLTLGILLGMFFVTWLPFFVANIVQAVCDCISPG
LFDVLTWLGYCNSTMNPIIYPLFMRDFKRALGRFLPCPRCPRERQASLASPSLRTSHSGP
RPGLSLQQVLPLPLPPDSDSDSDAGSGGSSGLRLTAQLLLPGEATQDPPLPTRAAAAVNF
FNIDPAEPELRPHPLGIPTN
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BDBM50402713 |
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n/a |
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Name | BDBM50402713 |
Synonyms: | CHEMBL2207379 |
Type | Small organic molecule |
Emp. Form. | C24H24ClN3O2S |
Mol. Mass. | 453.984 |
SMILES | CN1CCN(Cc2cccc3n(cc(Cl)c23)S(=O)(=O)c2cccc3ccccc23)CC1 |
Structure |
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