| Reaction Details |
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 | Report a problem with these data |
| Target | Cytochrome P450 2B1 |
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| Ligand | BDBM50404924 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_35524 (CHEMBL644757) |
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| IC50 | 309029.54±n/a nM |
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| Citation |  Murray, M; Ryan, AJ; Little, PJ Inhibition of rat hepatic microsomal aminopyrine N-demethylase activity by benzimidazole derivatives. Quantitative structure-activity relationships. J Med Chem25:887-92 (1982) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| Cytochrome P450 2B1 |
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| Name: | Cytochrome P450 2B1 |
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| Synonyms: | CP2B1_RAT | Cyp2b-1 | Cyp2b1 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 55940.51 |
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| Organism: | Rattus norvegicus |
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| Description: | ChEMBL_774167 |
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| Residue: | 491 |
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| Sequence: | MEPTILLLLALLVGFLLLLVRGHPKSRGNFPPGPRPLPLLGNLLQLDRGGLLNSFMQLRE
KYGDVFTVHLGPRPVVMLCGTDTIKEALVGQAEDFSGRGTIAVIEPIFKEYGVIFANGER
WKALRRFSLATMRDFGMGKRSVEERIQEEAQCLVEELRKSQGAPLDPTFLFQCITANIIC
SIVFGERFDYTDRQFLRLLELFYRTFSLLSSFSSQVFEFFSGFLKYFPGAHRQISKNLQE
ILDYIGHIVEKHRATLDPSAPRDFIDTYLLRMEKEKSNHHTEFHHENLMISLLSLFFAGT
ETSSTTLRYGFLLMLKYPHVAEKVQKEIDQVIGSHRLPTLDDRSKMPYTDAVIHEIQRFS
DLVPIGVPHRVTKDTMFRGYLLPKNTEVYPILSSALHDPQYFDHPDSFNPEHFLDANGAL
KKSEAFMPFSTGKRICLGEGIARNELFLFFTTILQNFSVSSHLAPKDIDLTPKESGIGKI
PPTYQICFSAR
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| BDBM50404924 |
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| n/a |
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| Name | BDBM50404924 |
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| Synonyms: | CHEMBL171730 |
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| Type | Small organic molecule |
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| Emp. Form. | C10H10ClN3O |
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| Mol. Mass. | 223.659 |
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| SMILES | CC(=O)Nc1cc(Cl)cc2nc(C)[nH]c12 |
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| Structure | 
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