| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Oxytocin receptor |
|---|
| Ligand | BDBM50407338 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_149195 (CHEMBL882485) |
|---|
| Kd | 10.72±n/a nM |
|---|
| Citation |  Manning, M; Cheng, LL; Klis, WA; Balaspiri, L; Olma, A; Sawyer, WH; Wo, NC; Chan, WY Effects of a D-Cys6/L-Cys6 interchange in nonselective and selective vasopressin and oxytocin antagonists. J Med Chem38:1762-9 (1995) [PubMed] |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Oxytocin receptor |
|---|
| Name: | Oxytocin receptor |
|---|
| Synonyms: | OT-R | OXYR_RAT | Otr | Oxtr | Oxytocin |
|---|
| Type: | Enzyme Catalytic Domain |
|---|
| Mol. Mass.: | 42889.28 |
|---|
| Organism: | RAT |
|---|
| Description: | Oxytocin OXTR RAT::P70536 |
|---|
| Residue: | 388 |
|---|
| Sequence: | MEGTPAANWSVELDLGSGVPPGEEGNRTAGPPQRNEALARVEVAVLCLILFLALSGNACV
LLALRTTRHKHSRLFFFMKHLSIADLVVAVFQVLPQLLWDITFRFYGPDLLCRLVKYLQV
VGMFASTYLLLLMSLDRCLAICQPLRSLRRRTDRLAVLGTWLGCLVASAPQVHIFSLREV
ADGVFDCWAVFIQPWGPKAYVTWITLAVYIVPVIVLAACYGLISFKIWQNLRLKTAAAAA
AAEGNDAAGGAGRAALARVSSVKLISKAKIRTVKMTFIIVLAFIVCWTPFFFVQMWSVWD
VNAPKEASAFIIAMLLASLNSCCNPWIYMLFTGHLFHELVQRFFCCSARYLKGSRPGETS
VSKKSNSSTFVLSRRSSSQRSCSQPSSA
|
|
|
|---|
| BDBM50407338 |
|---|
| n/a |
|---|
| Name | BDBM50407338 |
|---|
| Synonyms: | CHEMBL385062 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C51H73N13O10S2 |
|---|
| Mol. Mass. | 1092.336 |
|---|
| SMILES | CC(C)[C@@H]1NC(=O)[C@@H](Cc2ccccc2)NC(=O)[C@@H](Cc2ccccc2)NC(=O)CC2(CCCCC2)SSC[C@@H](NC(=O)[C@@H](CC(N)=O)NC1=O)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCNC(N)=N)C(=O)NCC(N)=O |
|---|
| Structure | 
|
|---|
Search and Browse
